ID A0A154PML2_DUFNO Unreviewed; 1001 AA.
AC A0A154PML2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Multiple epidermal growth factor-like domains protein 10 {ECO:0000313|EMBL:KZC13106.1};
GN ORFNames=WN55_05511 {ECO:0000313|EMBL:KZC13106.1};
OS Dufourea novaeangliae (Sweat bee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Halictidae; Rophitinae; Dufourea.
OX NCBI_TaxID=178035 {ECO:0000313|EMBL:KZC13106.1, ECO:0000313|Proteomes:UP000076502};
RN [1] {ECO:0000313|EMBL:KZC13106.1, ECO:0000313|Proteomes:UP000076502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0120121106 {ECO:0000313|EMBL:KZC13106.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KZC13106.1};
RA Pan H., Kapheim K.;
RT "The genome of Dufourea novaeangliae.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KQ434980; KZC13106.1; -; Genomic_DNA.
DR RefSeq; XP_015435605.1; XM_015580119.1.
DR AlphaFoldDB; A0A154PML2; -.
DR STRING; 178035.A0A154PML2; -.
DR EnsemblMetazoa; XM_015580119.1; XP_015435605.1; LOC107191153.
DR GeneID; 107191153; -.
DR OrthoDB; 2540323at2759; -.
DR Proteomes; UP000076502; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.10.25.140; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 5.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12661; hEGF; 4.
DR Pfam; PF00053; Laminin_EGF; 3.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 14.
DR SMART; SM00180; EGF_Lam; 13.
DR PROSITE; PS00022; EGF_1; 12.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076502};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1001
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007599687"
FT TRANSMEM 795..820
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..99
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 184..214
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 222..257
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 313..343
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 402..432
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 483..518
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 664..694
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 707..737
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 950..1001
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..987
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 204..213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 247..256
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 333..342
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 422..431
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 508..517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 684..693
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 727..736
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1001 AA; 110254 MW; 7008DB45EB8DECD1 CRC64;
MALTIWLIAA VAALCTTHAL EGPNICTRLD TYKVTVRISE QKPYTVRENT WCFSFPPRCS
KYKVVFKTVY KEQELTKQRP VEECCKGYTQ TNTGDRCIPV CSKDCVYGTC IAPDVCKCES
GYGGPICDFK CPSGKWGKSC QYECMCQNDA TCDPFDGKCM CTRGWTGKYC GEKCSPDRYG
QDCGEQCRCR NGGSCHHISG ECHCAPGYTG PLCDDLCPPG KHGDECKSEC KCQNGGSCNP
TTGECYCTTG WTGSVCANRC PEGFWGKKCS QSCDCYNEAG CHHITGECEC KPGYYGDKCL
KICAEGKFGL NCTDNCTCEN DALCSAVDGS CTCRPGWTGE KCEKRVCEDG YYGPNCSKVC
ECEGDNTELC HPWTGKCICK AGWDGDTCAR PCPFYTYGKG CQNHCDCKNN AQCSPINGTC
ICAAGYRGED CNEICPDNTY GENCGQKCVC KNGATCSPEN GRCNCTAGWV GVSCDRPCDN
KSFGKDCESK CKCFNNAACN PQNGTCTCAA GFTGELCQDR CKNGFFGHGC TQVCDCHDEN
SLDCEPATGR CICKPEWRGI RCETKCPEGL YGEDCHSQCE CMNNSSCDPE TGICICARGW
EGPNCSQPCK EGWYGVRCNE KCPEKMQGNM TCDHVTGEYV CRPGYLGLTC EHPCPPNRYG
VNCANHCRCK NGGECHHVTG VCQCRPGWHG EHCQTPCPEG TYGINCTQHC TCQNGGKCRS
NDGHCRCTPG WIGTKCNEIC PEGYYGDHCM KPCECKSDFY SCQPIKGCSC KHGYGGENCE
EELFSRNIQQ KEETGYGSIV AGFLFAAVVV IAMTLAGWVY HRRRVRDLKN EIAQVQYIAE
PPSPPEQTQF DNPVYAYQGS SKFDDGTTTL LNNFQFRNNL GTSKKINNEK VLFGMNGCID
EDDDCKGTYN RYDLKNRDAD MGNPNLNVYH TIDEMDGKKV EHVYDEIKQN NDESEYDQLE
NPRAVSTYKQ YNRMPNDSSS SSSDNAGPSK TKEKDPELGE T
//
