ID A0A154VI50_9PROT Unreviewed; 2132 AA.
AC A0A154VI50;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Non-ribosomal peptide synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AUP43_03675 {ECO:0000313|EMBL:KZD01049.1};
OS Oceanibaculum pacificum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Oceanibaculaceae; Oceanibaculum.
OX NCBI_TaxID=580166 {ECO:0000313|EMBL:KZD01049.1, ECO:0000313|Proteomes:UP000076400};
RN [1] {ECO:0000313|EMBL:KZD01049.1, ECO:0000313|Proteomes:UP000076400}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A02656 {ECO:0000313|EMBL:KZD01049.1,
RC ECO:0000313|Proteomes:UP000076400};
RA Lu L., Lai Q., Shao Z., Qian P.;
RT "Genome sequence of Oceanibaculum pacificum MCCC 1A02656.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZD01049.1}.
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DR EMBL; LPXN01000160; KZD01049.1; -; Genomic_DNA.
DR RefSeq; WP_067559873.1; NZ_LPXN01000160.1.
DR STRING; 580166.AUP43_03675; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000076400; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076400};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 993..1068
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1097..1522
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2023..2098
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 2109..2132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2132 AA; 224359 MW; 9A18929C2CC4067C CRC64;
MDSPDHRADR GSALTAPQAG MWLDGAGDPV SAKYTIGNYV RLVGDLDVEA LCRALTQTDA
ESDCAQLRFG QHDGLPFQYL AEKAAPTDFA VIDLRHAPDP AAAARLEMEA FRRRPFDKGA
GPLCGHRLLR LGPDEHWWFR SYSHLITDGL SSHILAERTA QIYNASKRGE APPDAWFGRY
TDFIAEEEAY PGSAAYERDV AYWRERLANA EPASRFKPGA GATSTEIAEF LARLDAGRIA
GLQALAERSK ASLAALAMAL YYLLLGRMAG TQRPTALTPF GNRIGRQERS TPGAFAFALP
FTVDLAGKHD IGDLAREIFG QLRRDMRHMR LAPIRMRAAL GGSSRPDADG AGVNIIGVVP
PLAFDGLSAS VVNFYTGLAS DISLIFVGEE LGDGGTGAYL HWRYNPALYT RAEVARIAAR
FEHLLDRVLA NPDQPLADLT LTPEAEIATI RRWEAGPAIP PDMQAPLLPA RIADVMRRFP
DHVAVIADDG TETHYGQLDR LASAISRNLL EAGVQRGDLV GLGCLPGPAL VAGLIALWRR
GAAAVMLDPV LPIARRRAMA ETIDVRLVLC DAATLWPDAD RGAIQAVDLT GWMTEAAGRT
AGEEPAGEGV EPADDDIAIV FHTAGSTGQP KPVAVPHGAL CRKVVSVAGH YSLGSADAGD
PETVVLSPAM GFDPWIQELG MALITGARLW TMRRETLLDG HRFWNEATRH GATYINLTPT
AMESLIDSAP LDGGHAVRHV VLGGEIFSPG LAARLRAVLG DAALWNGYGP TETVVDITAY
RLPHRFSDDR VPIGPVSPGG LVRVIGPDGR RAPIGMQGEL YLGGACVSLG YIGMPEATAA
AFLPDPVGEV EGVFYRSGDL ASWGEDGALT YRGRNDSQVK VRGQRIELGE VESNLRRLPG
IAQAAVLHVG DAHGGHLRAF VTRAPDGGGD IAPASIRLAL ARTLPEAAIP SIAVLESLPY
LPSGKIDRAA LAALPEQAAA AAAPARALPG FSAREHQVQQ AVAAVWRELI GAGEIDPQAN
LFDIGAHSLL VLRAQGRLGR IAGREVSAVE IFEHPSIAAF ARYLTHGSNI AAPAAAPGAA
SGAAPGAAGQ PQAVERPGAI AIIGMGMRLP GADNRADFWA LLEAGRDCVR DIDAARLRAF
GVDPSLLQDP GFVARHGLLE DIDGFDPIPF GMTSADALET DPQQRLLLET ALTALEDASC
DPARDGPVGV YVGVGFPTCL LDALAPQRTG NTLDMARYAL ALGNDKDHAA TRLAYKLNLT
GPAIAAGTAC STGLVNVASA VQALRAGQCR VALAGGAAFG TGVTGGYRYA EGGIGSRSGI
CRPFDSQADG VVGGSGAAIV ALKRLEDALA DGDTVHAVIL GVGLSNDGAR KAAFTAPSVE
GQAAALSAAL ADAGVAPGSV RFIEAHGTAT SLGDPIEVAA LNKVYGPRQE RPIWLGSLKG
NMGHLDTAAG IAGLLKAVLA LQHRLVPPSC NFQQPNPRIP FDQGPFQVAD RPVPLDADET
PLRAGVSSFG VGGTNAHVIL EAAPPRPNAA AAAALAKPQI LVFSAASEKP LDALLRLTAD
ALGGDLASAG LTDIAFSLRA RRRYPHRVAI LARDTAEAVA ALRAPDHPGH IRAIAAKSTP
PVAFLFPGQG SQSPGMAAAL YRDDAAIRDR IDRACAAVTA MGGPVDLHDL LLTDRRDADS
VARMARTEIA QPALFIVSYA IAERLMAYGV RPTALAGHSI GEYAAACLAE VMSFDDALRL
VTLRGRLMGQ SGPGAMLALP ATEPEVVELL SAVAPTLSLA AVNGPRQCVV AGQPEEIDAL
EAHLRAIGKP GQRLTVSHAF HSATMEPILE AFRAEAAKTA LYAPAIPLQS NLTGDWLSDA
NARSPDYWTR HLRHSVRFAD NMNSLLARFP DSLAIECGAG RTASRLAQIN GLAGDRAVAS
QPFDRTQPAM DGETALLQAV SRLWAQGVEP DWSSMAPAGE RRRIPLPTYP FDRKRFWPEV
FQRDAAQPEA ARNGAAHGHL SATLQFSAAN DAALGAGQQA GEQPTRDTLE TVISVWYRLF
GDTTIGAHDD FLERGGDSLL AVRIASILSA ELGTDIPVAE LFEGRTPAEM AARIDARFAR
SATPPIGAAP AGGAIDRPAA VGEGKPRERG VL
//
