ID A0A154WHA7_9PROT Unreviewed; 330 AA.
AC A0A154WHA7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=D-glycerate dehydrogenase {ECO:0000313|EMBL:KZD12901.1};
GN ORFNames=AUP43_00765 {ECO:0000313|EMBL:KZD12901.1};
OS Oceanibaculum pacificum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Oceanibaculaceae; Oceanibaculum.
OX NCBI_TaxID=580166 {ECO:0000313|EMBL:KZD12901.1, ECO:0000313|Proteomes:UP000076400};
RN [1] {ECO:0000313|EMBL:KZD12901.1, ECO:0000313|Proteomes:UP000076400}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A02656 {ECO:0000313|EMBL:KZD12901.1,
RC ECO:0000313|Proteomes:UP000076400};
RA Lu L., Lai Q., Shao Z., Qian P.;
RT "Genome sequence of Oceanibaculum pacificum MCCC 1A02656.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZD12901.1}.
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DR EMBL; LPXN01000001; KZD12901.1; -; Genomic_DNA.
DR RefSeq; WP_067551220.1; NZ_LPXN01000001.1.
DR AlphaFoldDB; A0A154WHA7; -.
DR STRING; 580166.AUP43_00765; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000076400; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000076400}.
FT DOMAIN 19..325
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 115..294
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 330 AA; 36502 MW; CC7F81CA79C3FA4B CRC64;
MPTSVKKPIV VVTRKLPDAI ETRMMELFDA RLNLDDRPMS PAELIEAVKV AEVLVPTVTD
RVDARIMAQA GPQLRLIASF GTGVDHIDLA TARQRGVTVT NTPGVLTEDT ADMTMALILA
VSRRLTEGER LVRAGSWEGW GPTLMLGHRI WGKRLGIIGM GRIGQAVARR ARGFGLSIHY
HNRRRVHPDI ENELEATYWD SLDQMLARMD VISINCPHTP ATYHLLSSRR LKLLRPTSIV
VNTSRGEVID ENALAKSLAG RELAGAGLDV FEHEPAVNPK LLELDNVVLM PHMGSATIEG
RIDMGEKVII NIKTFVDGHT PPDRVLEQMF
//
