ID A0A157SKY0_9BORD Unreviewed; 386 AA.
AC A0A157SKY0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN Name=echA8_10 {ECO:0000313|EMBL:SAI71128.1};
GN ORFNames=SAMEA3906486_03369 {ECO:0000313|EMBL:SAI71128.1};
OS Bordetella ansorpii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=288768 {ECO:0000313|EMBL:SAI71128.1, ECO:0000313|Proteomes:UP000076848};
RN [1] {ECO:0000313|EMBL:SAI71128.1, ECO:0000313|Proteomes:UP000076848}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H050680373 {ECO:0000313|EMBL:SAI71128.1,
RC ECO:0000313|Proteomes:UP000076848};
RG Pathogen Informatics;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; FKIF01000007; SAI71128.1; -; Genomic_DNA.
DR RefSeq; WP_066129420.1; NZ_FKIF01000007.1.
DR AlphaFoldDB; A0A157SKY0; -.
DR STRING; 288768.SAMEA3906486_03369; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000076848; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lyase {ECO:0000313|EMBL:SAI71128.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076848}.
FT DOMAIN 19..368
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 386 AA; 42279 MW; 7B06C66C3DA112C5 CRC64;
MNVPVLFEER FTDTGMRLGV ATLNSPQTLN GLSLEMVDML DAQLRAWAAD SSVALVILQG
AGEKAFCAGG DLHGLYRSMR EHAGQGAWAN THARTFFEHE YRLDFLIHCY PKPLLCWGRG
IVMGGGVGLM MGASHRVVSS DARVAMPEIS IGLFPDVGAS WMLNRMPGRV GLFLALTGAH
LNTSDAFFAG MADFRLDPAD WPRFCEALLH QPWAGGPNQG GLAPRSINDG LLRQVLLAHE
PSEPLEPGPL RQHSFLINSI CGEMKLETIY DELAGLTNHD DPWLARAAKT MLAGSPGSAR
LAYALQQHTR LRSLDDVFRI EYVAALVCTA HGDLEEGIRA LLVDKDKTPR WNPATLAEAS
PAWVQQFFQE PWPEGVPHPL EDLGRA
//
