ID   A0A158BEI2_9BURK        Unreviewed;      1000 AA.
AC   A0A158BEI2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:SAK68469.1};
GN   ORFNames=AWB79_03557 {ECO:0000313|EMBL:SAK68469.1};
OS   Caballeronia hypogeia.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Caballeronia.
OX   NCBI_TaxID=1777140 {ECO:0000313|EMBL:SAK68469.1, ECO:0000313|Proteomes:UP000054851};
RN   [1] {ECO:0000313|Proteomes:UP000054851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Oliw E.H.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; FCOA02000011; SAK68469.1; -; Genomic_DNA.
DR   RefSeq; WP_061168739.1; NZ_FCOA02000011.1.
DR   AlphaFoldDB; A0A158BEI2; -.
DR   STRING; 1777140.AWB79_03557; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000054851; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          170..431
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          518..600
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          616..879
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          905..991
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   1000 AA;  108915 MW;  B869B693E18E4578 CRC64;
     MSQKDRLGMG GRINRAIPVT FTFNGKTYQG FEGDTLASAL LANGERFVAR SWKYHRPRGI
     ITAGVEEPNA VVQLETGTYT VPNARATEVE LYQGLVAQSV NAKPSIEKDR MAVNQKIARF
     IPAGFYYKTF MWPRKFWPKY EEVIRDAAGL GEAPKQLDAD RYDKCFAHCD VLVVGGGPSG
     LAAAHAAALS GARVILVDDQ RELGGSLLSC RAEIDGKPAL QWVQKIEAEL RKMPDVKILS
     RSTAFGYQDH NLVTITQRLT EHLPVSRRSG TRELMWKVRA KRVILATGAH ERPIVFGNND
     LPGIMLASAV STYLHRYAVL PGRNAVVFIN NDDAYQCALD LKAAGAEVTI VDPRPAESKG
     TLPALARRQG LRVLNNAVIT VARGKLRVAS VEVSSYANGQ VGQKQSDLPC DLVAMSGGWS
     PVLHLFAQSG GKAHWHDEKA CFVPGKAMQA ESSVGACAGE FTLARGLRSG VEAGADAARA
     AGHIVAKPQP VKVAEIVEAP LMPLWIVGNK DMATRGPKQF VDFQNDVSAA DIYLAAREGF
     ESVEHVKRYT AMGFGTDQGK LGNINGMAIL AGALGKTIPE TGTTTFRPNY TPVTFGTFAG
     RELGEFLDPV RKTAIHEWHV ENGALFEDVG NWKRPWYFPK NGEDMHAAVA RESLAVRQSV
     GILDASTLGK IDIQGPDSAK LLNWMYTNPW SKLEVGKCRY GLMLDENGMI FDDGVTVRLG
     EQHYMMTTTT GGAARVLTWL ERWLQTEWPD MRVRLASVTD HWATFAVVGP NSRKVLQKVC
     HDIDFANGSF PFMSYRDGTV AGAAARVMRI SFSGELAYEV NVPANVGRAV WEAIMLAGAE
     FDITPYGTET MHVLRAEKGY IIVGQDTDGS MTPYDLGMGG LVAKSKDFIG KRSLTRSDTA
     KQGRKQFVGL LTDDPQYVLP EGAQIVAGPF QGDTAPMLGH VTSSYYSPIL KRSIALAVVK
     GGLEKIGESV MIPLANGKRI NAKITSSVFY DSEGARQHVE
//