ID A0A158CZF5_9BURK Unreviewed; 836 AA.
AC A0A158CZF5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AWB78_04538 {ECO:0000313|EMBL:SAK87470.1};
OS Caballeronia calidae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=1777139 {ECO:0000313|EMBL:SAK87470.1, ECO:0000313|Proteomes:UP000071859};
RN [1] {ECO:0000313|EMBL:SAK87470.1, ECO:0000313|Proteomes:UP000071859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 29321 {ECO:0000313|EMBL:SAK87470.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FCOX02000025; SAK87470.1; -; Genomic_DNA.
DR RefSeq; WP_062608146.1; NZ_FCOX02000025.1.
DR AlphaFoldDB; A0A158CZF5; -.
DR OrthoDB; 9768069at2; -.
DR Proteomes; UP000071859; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SAK87470.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 213..284
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 338..393
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 413..465
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 475..694
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 715..834
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 764
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 836 AA; 90953 MW; F172ED18E72F3463 CRC64;
MRTRYEASTP ENKIKAEQKR QANFQKWFVT FASLAHSRLP LSAYLQKVTD TLREVADVGS
AVVEWIEGDT LIYRAASGAA SAHIGTRLPT SGSLSGLCIT RQQALICRNA ATDHRVDRAA
CEAVGAVSMV VAPVVYEGRS VAVLKLISGE VDRFAQSDIS ILDAFCACIA ETIAREDIAQ
ENRQLVKQNA SVAADLSVES SLRTEYEKRL ADAMRRRQTV LDNAHVAFVS MDEAGMVVDW
NEAAALLFGW KAQEVAGREL ASFIVPERLR DMHRKGLTRY LATGEARMIN KRVELPALRR
DGSEFAAELT ISEVWYEGQR QFACFVHDIT DRLVATEANE RLRLLINSVS DYAICMLDED
GYVRSWNDGA RAIYGFTADE AIGRHFALFY TSDEQGRDRP GDDLALAAKR GRVEHEDWHV
RKDGSEFWAH VILSALPNAN GGEQGFVKIT RDMTARRRLE ELEASSRRMN EFLALLGHEL
RNPLAPIRNA VSILKLKASD DADVIRSRQI VDRQLAHLTQ LVDDLLEAGR VSSGKIRLTT
DIVDIADVVH LSVEASQPLC DERGQRIVVQ DSGQPLFVNG DSTRLVQALN NLLNNASKFS
PHGATITLET GPRGGSAMVR VIDEGRGISA DALGIVFDLF VQEHPPGAHP DESGLGIGLT
LVRAIAELHG GHVEAKSGGA GQGSAFSLWL PLAEPPVRGA SAGAPPSVAA SRQLDVLVVD
DNRDSADSMT LLVDMLGHQA RAAYDGPGAL DSFDASRPQV VLLDLSMPGM TGFDVIRRMR
DGGSTRGGQR VIVAAMTGLG SDEDIARTRA AGFDAHLVKP VDLPELERVL ALAGRA
//
