ID   A0A158FLS1_9BURK        Unreviewed;       410 AA.
AC   A0A158FLS1;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Secretion protein HlyD family protein {ECO:0000313|EMBL:SAL20637.1};
GN   ORFNames=AWB65_01035 {ECO:0000313|EMBL:SAL20637.1};
OS   Caballeronia humi.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Caballeronia.
OX   NCBI_TaxID=326474 {ECO:0000313|EMBL:SAL20637.1, ECO:0000313|Proteomes:UP000054977};
RN   [1] {ECO:0000313|EMBL:SAL20637.1, ECO:0000313|Proteomes:UP000054977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 22934 {ECO:0000313|EMBL:SAL20637.1};
RA   Oliw E.H.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; FCNW02000003; SAL20637.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158FLS1; -.
DR   STRING; 326474.AWB65_01035; -.
DR   OrthoDB; 9811754at2; -.
DR   Proteomes; UP000054977; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR043602; CusB_dom_1.
DR   InterPro; IPR032317; HlyD_D23.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR   Pfam; PF00529; CusB_dom_1; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        23..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          60..289
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   DOMAIN          290..345
FT                   /note="Cation efflux system protein CusB"
FT                   /evidence="ECO:0000259|Pfam:PF00529"
FT   REGION          387..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   410 AA;  43758 MW;  FBA2847087ACB08D CRC64;
     MSDPQQTAAA PAPKTNTTKR RTLMTLIVLV IIIAAVAYGL YYFLVARFHE STDDAYVNGN
     VVQITPQVVG TVTSVNADDT QTVKVGDPLV VLDPADSKVA LDQAEANLAQ TVRQVRTLFV
     NDNQYEAQVA LRRSDLSRAQ DDLRRRMTIA QTGAVSQEEI SHARDAVRSA QAGLDAAQQE
     LASNRSLTAN TTIAGHPNVL AAAAKVRDAY INYARNTLPA PVTGYVAKRS VQVGQRVAPG
     NPLMAIVPLN AVWVDANFKE VQLKHMRIGQ PVELTADLYG SGVVFHGKVI GFSAGTGSAF
     SLLPAQNATG NWIKVVQRLP VRVALDPKEL EQHPLRIGLS MNADVTIKSE EGGQLGTAPN
     TVYQTNVFDK YGDQADAEIA RIIQQNAGSG GGAQSSVSRG NAKPAAAKLM
//