ID A0A158HB48_9BURK Unreviewed; 1385 AA.
AC A0A158HB48;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AWB69_04140 {ECO:0000313|EMBL:SAL40970.1};
OS Caballeronia udeis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=1232866 {ECO:0000313|EMBL:SAL40970.1, ECO:0000313|Proteomes:UP000054683};
RN [1] {ECO:0000313|EMBL:SAL40970.1, ECO:0000313|Proteomes:UP000054683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 27134 {ECO:0000313|EMBL:SAL40970.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FCOK02000027; SAL40970.1; -; Genomic_DNA.
DR RefSeq; WP_063977861.1; NZ_FCOK02000027.1.
DR OrthoDB; 9816309at2; -.
DR Proteomes; UP000054683; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd16434; CheB-CheR_fusion; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.180; Methylesterase CheB, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035909; CheB_C.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR000673; Sig_transdc_resp-reg_Me-estase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF25; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF01339; CheB_methylest; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13596; PAS_10; 1.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00138; MeTrc; 1.
DR SMART; SM00091; PAS; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52738; Methylesterase CheB, C-terminal domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50122; CHEB; 1.
DR PROSITE; PS50123; CHER; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500, ECO:0000256|PROSITE-
KW ProRule:PRU00050}; Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00050};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 21..211
FT /note="CheB-type methylesterase"
FT /evidence="ECO:0000259|PROSITE:PS50122"
FT DOMAIN 248..487
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT DOMAIN 877..948
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1027..1246
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1267..1383
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 676..745
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 34
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
FT ACT_SITE 61
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
FT ACT_SITE 153
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
FT MOD_RES 1316
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1385 AA; 152771 MW; 056E489B522F2D66 CRC64;
MTIRKQPGAQ IISSSDSLPN PHPIDFPVVG IGASAGGIQA LMRLLQGMPA DGGMAFVVVL
HIPPDYASHV DEVLQRSVTM PVVQVFDTTP IEKNTVYLIS PANDLWLSEG CLRVTPSDQS
RRRPVAIDLF FRSLADAHRA RAISIILSGM GSDGAMGIAR IKEQNGINIV QDPLDAEYDE
MPRNALATGF VDIVLSVERM PARLIELRDS ARAMKTLHAV DDLPRNEPGV EPPVSNLDAD
ADADADVLQA LLTILRIRTG HDFRHYKRGT MMRRIERRLQ VNGVADLAGY KRFIETHPEE
TTALLKDMLI GVTNFFRDRK SFDAFGQQVV ANLFTGRSPD EPVRAWSAGC STGEEPYSLA
MLLTEHGPAH GKFPLIQVFA TDVDASAIDT ARAGVYAGSI VADVSPERLS RFFVKPGGRY
QVSKELRQKV VFAVHNILSD PPFSGMDVVS CRNLLIYLDR TVQRQVLEMF HFALRPGGFL
FLGGAESTEI ARDLFEQVDK RNRIYQSKRI GTRAMPPLPL IRPAIFDIPR RPGPRRDTLA
SLAALRQRVF ERYAPPNVTV DRDGVILHMS DRAGRFLQYV SGEPSRNLLT LVNPELRAEL
RTTLHCVLRD GDSVVSRRVR FSRGEKLSFV NISARPFKDD DSGQEVIVVF FDEFENETVV
QQDVPARGDT PDAAKLVDLE QDLYRTQTQM DSLTEDASVS SEELMASNEE LQAINEELRS
TTEELEAGKE ELQSVNEELV TVNLELSETV AETVKANDDL RNLISSTGIP TVFVDRAMRI
KRYTPPAVGI FKLIASDIGR PLLDLTHRLD YPQMAADARA AFDTLTLTER EIRTDRGEWY
LARVLPYRTA DDQIDGAVIT LIDITARKAA EAAARSSEER LRLAAITTND YAIIVLDMDG
VIVTWNGGAQ RIFGYAENEV QGQPLDLIFL PADREARVPL LERQRASQAG RAEDERWHVR
SDGTEIYCSG VTTPIESDLF RGYAKISRDV TDRTGIESQK QLALTLERAI RAQSEAADRL
KDEFFSVLSH ELKNPLNLIH VKAELLTRIP DVRDISIVQD AADAIQRAVA GQARIIDDLL
DLSRVRTGKL ALRFAPVEVA SVLQAVVAAS AADAQAADIE LSAGTSAAVM IHADAERVEQ
MIWNLVRNAL KFTPHGGRVR IALSRASGFV CVEVVDTGQG IDPGFLPRIF EMFSQADGGG
RRDRGGLGIG LSLVKQLAEL HGGRIEAESA GPGQGAHFRL WLPENAPLPL VETAREYVDP
GILKGLRVLL VDDSVEALEA FRTLLEMEGA QVRAEPSAEQ ALEAVAQQEF DVVLSDIGMP
TMNGYEMIQQ MRRTPRTAQL PALALTGFGR EQDVTRALDA GFNGHLSKPV SLKGLVAAID
RSLRR
//
