ID   A0A158JMF3_9BURK        Unreviewed;       510 AA.
AC   A0A158JMF3;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Tyrosinase {ECO:0000313|EMBL:SAL69928.1};
DE            EC=1.14.18.1 {ECO:0000313|EMBL:SAL69928.1};
GN   Name=melC2_3 {ECO:0000313|EMBL:SAL69928.1};
GN   ORFNames=AWB65_06878 {ECO:0000313|EMBL:SAL69928.1};
OS   Caballeronia humi.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Caballeronia.
OX   NCBI_TaxID=326474 {ECO:0000313|EMBL:SAL69928.1, ECO:0000313|Proteomes:UP000054977};
RN   [1] {ECO:0000313|EMBL:SAL69928.1, ECO:0000313|Proteomes:UP000054977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 22934 {ECO:0000313|EMBL:SAL69928.1};
RA   Oliw E.H.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FCNW02000156; SAL69928.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158JMF3; -.
DR   STRING; 326474.AWB65_06878; -.
DR   Proteomes; UP000054977; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004503; F:tyrosinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 2.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR006311; TAT_signal.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF76; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 2.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS51318; TAT; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000313|EMBL:SAL69928.1};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..510
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011108635"
FT   DOMAIN          82..99
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          194..205
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   510 AA;  56282 MW;  489199E54F7CD586 CRC64;
     MSYLKLNRRT FLGGAASALS LAAFPRFAEA AGSVRLGWQQ FKATPQYSSF LHAVQTMRAN
     KNANDPGSWQ YWVNVHVNYC PHKTNYFLAW HRGYLWWLEQ QLKTFDQNLM LPYWDWYTNP
     TVPTEFTNAA TGNALYVPRV NTNVYSALDL SPFSAANFQR GTVNSFEDGF ETRPHNPVHN
     LIGNVMSSMV SPSDPIFFLH HCNIDRLWHA WAMPDGRTMP ATSAPYWTTQ TTPPIFTYAP
     NKTMPKDQTY APRRQGAVWP NRTPYDYANT ARPQVLPLQS QVGRIIRVQG QGRDLTRPPI
     AFTAGTPPRD VTADRRSIGG VKGVALREQS VSALVTAEAS SVQPLQDVIA TTTTEFPEAE
     TTDPSAPAPA ASSAAKAKKF RSVKIVLDNI KITGAGTVGG YFYNVYLDLP DNADIETASS
     KHLLGTLGAF EIAGESHHGS VTLEYPATGA LVRMRAKSTR EHVISFVRVS GATAPAGEVI
     AVGEVRVELT TEVPFVKSKR VKPGRDDVPY
//