ID A0A158NAK2_ATTCE Unreviewed; 615 AA.
AC A0A158NAK2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Equilibrative nucleoside transporter 4 {ECO:0008006|Google:ProtNLM};
GN Name=105617615 {ECO:0000313|EnsemblMetazoa:XP_012054560.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012054560.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012054560.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR EMBL; ADTU01010342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01010343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012054560.1; XM_012199170.1.
DR AlphaFoldDB; A0A158NAK2; -.
DR EnsemblMetazoa; XM_012199170.1; XP_012054560.1; LOC105617615.
DR GeneID; 105617615; -.
DR KEGG; acep:105617615; -.
DR eggNOG; KOG1479; Eukaryota.
DR InParanoid; A0A158NAK2; -.
DR OMA; ARGMNEF; -.
DR OrthoDB; 2939652at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002259; Eqnu_transpt.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF89; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4; 1.
DR Pfam; PF01733; Nucleoside_tran; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 39..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 615 AA; 67098 MW; 5BA39653583EAC1C CRC64;
MDENLSRGYV QLGKARGMNE FKFSNGFTHL SPPVDKCNFI YMALILGGIG FLLPYNSFII
AVDYFQARYP GTTVIFDMSV VYIIMAFFAV FANNILVETL SLNTRITFGY LVSFVTLNFV
VICEIWWELF GVATSYTINL VAVAIVSLGC TVQQSSFYGY TSMLPSRYTQ AVMTGESFAG
FWVSINRIIT KSLLNDERGN TSMFFILSNM TILLCFVLHQ VVRKTDFVQF YITLCQERNR
ITLEPTEDVG LMDPLDQVGD PSKGQYGVLK IQTSPLGTES ASGSADLNAA GQYSAFSFSN
PVYEPSAPSG NPPGSAGPTY KVEDVVVMRG AYGTQSTSTP WSGIKRGLLA RLEVAKLIFP
YMVSIGAAYF ITLCLYPGIV SEIISCKFES WMPVILMTAF NASDLLGKVF ALIPYEWKRT
QLLYFSSARI ILIPLFFLCA IPRGAPILSG EGYPLLFSWL LGLTNGIVGS IPMIQAPSKV
PEEHRELAGN IMTLSYTTGL TIGSLLAYMM DACLGPPVQI KDVCLKTAKV QTSTTVFSNV
TASILTTAIS STLPIVEKTT AISKPKTTDV LTTILMSTLL SNSTVSDRGL SDASTTALPK
ILANVTSASN AILQH
//
