ID A0A158NB18_ATTCE Unreviewed; 360 AA.
AC A0A158NB18;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Protein artemis {ECO:0000256|ARBA:ARBA00039759};
DE AltName: Full=DNA cross-link repair 1C protein {ECO:0000256|ARBA:ARBA00042677};
GN Name=105617782 {ECO:0000313|EnsemblMetazoa:XP_012054726.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012054726.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012054726.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
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DR EMBL; ADTU01010746; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012054726.1; XM_012199336.1.
DR AlphaFoldDB; A0A158NB18; -.
DR STRING; 12957.A0A158NB18; -.
DR EnsemblMetazoa; XM_012199336.1; XP_012054726.1; LOC105617782.
DR GeneID; 105617782; -.
DR KEGG; acep:105617782; -.
DR eggNOG; KOG1361; Eukaryota.
DR InParanoid; A0A158NB18; -.
DR OMA; NVCYSTH; -.
DR OrthoDB; 23465at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF38; PROTEIN ARTEMIS; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205}.
FT DOMAIN 244..345
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
SQ SEQUENCE 360 AA; 42469 MW; 5DB1E92F78837D73 CRC64;
MSTFVGLIKE IPGISVDRFD RENMNSSVYF LSHCHIDHMC GLNNMFFDHL KQYNKYLYCS
RITKVFLENK YYENLRNVET YVKDIEVDKK ICIEYRSNYN SEETDILFVT FTSAGHCPGS
VMFVFEKMNK LILYTGDFRI NPKDYYKIKS LNYCNNFPKK FDNVYLDTTF LGHDFTYLPT
RIESINVMCK VVKKWLDESP RKVVILECSA LYGSEFLYME LSKSLKTLIH VKEYVYNSYI
RIPELACHVT NNPLDARIHA CMSKSTCMNR SGLRCRTNVL QQDILTIVPS VKKWKGRDTS
VIGEWDKFSE KTFNVCYSTH ASFDELKEFI QYFKPKNIHP CVCPENEQDT INRLLDEIRR
//
