ID A0A158NBF0_ATTCE Unreviewed; 673 AA.
AC A0A158NBF0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Pickpocket protein 28 {ECO:0008006|Google:ProtNLM};
GN Name=105617931 {ECO:0000313|EnsemblMetazoa:XP_012054858.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012054858.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012054858.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC ECO:0000256|RuleBase:RU000679}.
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DR EMBL; ADTU01000293; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012054858.1; XM_012199468.1.
DR AlphaFoldDB; A0A158NBF0; -.
DR STRING; 12957.A0A158NBF0; -.
DR EnsemblMetazoa; XM_012199468.1; XP_012054858.1; LOC105617931.
DR GeneID; 105617931; -.
DR KEGG; acep:105617931; -.
DR eggNOG; KOG4294; Eukaryota.
DR InParanoid; A0A158NBF0; -.
DR OrthoDB; 3414706at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR Gene3D; 1.10.287.770; YojJ-like; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR PANTHER; PTHR11690:SF243; PICKPOCKET 12-RELATED; 1.
DR Pfam; PF00858; ASC; 1.
DR PRINTS; PR01078; AMINACHANNEL.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 129..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 78411 MW; EFCDEB12CEEAAB89 CRC64;
MEDSLKRKKR KAILNPWNDA QILTHVMNVD RASDFVNMKI FNTPMMSSRT YNRNHPSDEK
YYNDADGAQF DLKTSNTIPS YSVNTVHLQN PYRPPQQLEG FASRDHLKDM YQLQDFTLRS
RYNNNLFAKE SATNKNNNQE SEKTEKLKTG KKHQKLTEIG ELAKQYCSCS SLHGLRYVGD
SGLSIVERIF WIISFTIALT VAIYYICYIY QKWNGSPIII SLSPDPISLN EFPFPSVTIC
NMNKIKKTEG KRIERGFDEL DKLLVEDRCN SDSNITYEDH DDQAINWDKM LKFMINVTQP
CTDMIYYCLW HGISTECERI FNPTMTDEGI CCNFNSVARK HLFYNPLDWS DLNITYPSES
VDWNAEKGYD ASMSPDVIPW RPYGAGLTYG LTLALDVDID EYYCSSTAGA GFKMLLHNPV
ETPKIADFSF SITPGEETRI IIRPRISYAN PSIISIAQKK RKCFFMSERK LRYYRTYTQR
NCILECEANY TKKLCNCVQY YMPKSSNTPI CGKKDEPCAK RARQDMEIKL YDEVLNNITI
PSCNCWPACF EINYRIELSQ NKLVQTFQTN KQYVKKNIDY FTENVAVVHL FFVDSQFTKY
MKSELFGFIE FLSSTGGLLG LFMGFSFLSF MEILYFSTMR VWCRFNNRRE MQRPNVLQTH
PLDNKKVIYP FIN
//
