ID A0A158NDP3_ATTCE Unreviewed; 356 AA.
AC A0A158NDP3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=105618731 {ECO:0000313|EnsemblMetazoa:XP_012055651.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012055651.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012055651.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR EMBL; ADTU01012741; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012742; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012743; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012744; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012745; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012746; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012055651.1; XM_012200261.1.
DR AlphaFoldDB; A0A158NDP3; -.
DR STRING; 12957.A0A158NDP3; -.
DR EnsemblMetazoa; XM_012200261.1; XP_012055651.1; LOC105618731.
DR GeneID; 105618731; -.
DR KEGG; acep:105618731; -.
DR eggNOG; KOG3913; Eukaryota.
DR InParanoid; A0A158NDP3; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19338; Wnt_Wnt6; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR009143; Wnt6.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF72; PROTEIN WNT-6; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..356
FT /note="Protein Wnt"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007629014"
SQ SEQUENCE 356 AA; 39986 MW; B5A74421DDC205A3 CRC64;
MEMRPVLVAI CLLLVTPITG SFWTVGSQLV MDPMLVCKKT RRLKGKLADI CRKEPSLLKE
IAKGVQVGTR ECQYQFRNRR WNCTTVRRSL KKILLRDTRE TGFVNAITAA GVTYAVTRAC
TMGDLVECSC DKMTSKGNRL AKFARTVEAK KSLPTEGDWE WGGCGDNVNF GFKKSREFMD
APYRKRSDIK TLVKLHNNDA GRLAVRNFMR TECKCHGLSG SCTVRTCWRK MPPFREVGNR
LKESFDGAAK VIPSNDGHSF ITEGPTIKPP GRFDLIYSED SPDFCKPNRK TGSLGTTGRQ
CNSTSPGVEG CELLCCGRGY DTRIVKEKVN CQCRFRWCCE VTCNTCLVKK TVNTCR
//
