ID A0A158NDP7_ATTCE Unreviewed; 1271 AA.
AC A0A158NDP7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
GN Name=105618734 {ECO:0000313|EnsemblMetazoa:XP_012055655.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012055655.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012055655.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
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DR EMBL; ADTU01012762; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01012764; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012055655.1; XM_012200265.1.
DR AlphaFoldDB; A0A158NDP7; -.
DR STRING; 12957.A0A158NDP7; -.
DR EnsemblMetazoa; XM_012200265.1; XP_012055655.1; LOC105618734.
DR GeneID; 105618734; -.
DR KEGG; acep:105618734; -.
DR eggNOG; KOG1172; Eukaryota.
DR InParanoid; A0A158NDP7; -.
DR OrthoDB; 1013180at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF36; ANION EXCHANGE PROTEIN; 1.
DR Pfam; PF07565; Band_3_cyto; 2.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 604..626
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 638..657
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 694..720
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 727..747
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 807..825
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 845..865
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 897..916
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 937..961
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 997..1016
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 1023..1049
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 160..270
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 394..532
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 580..1075
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1192..1237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1209..1237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1271 AA; 141712 MW; 01F15A5F5431B03C CRC64;
MQPRAGSGGA HPGGTGDDEA PKDPGARITH QSYTEKDYEG HRAHTVYVGV HLPGERRHRR
HHKHHHSQRQ PYPCGKEDAD NDRPRQFLMA RRGRLASICD PAGEMIFTPP AQRVQFILGE
EVGDDAHESH PLFSEMEELI KDGDEMEWKE TARWIKFEED VEEGGNRWSK PHVATLSLHS
LFELRSLLLN GTVMLDMEAG SLEQIADLVL DNMINKGVLL VELREKVREA LLVRHRHQHE
RRKDNNMSKL PIIRSLAEIG RNHSSSKNSD CSCGMHALLT SDLQERRDPK DIYVPSVARS
SSCPNSNMAP LSKEAKDLKG PYLLVPDEFG IPHVVGFTTW FAMCPLKVEE SNSAPAIAGA
TSQGSGAALN AGSRFLAIPG QEPGSNGMDR SPSSVSISRN HSSSALENGD VNHKGNTHFM
RKIPAGAEAS NILVGEVDFL DKTLSAFIRL SQAGIMGDLT EVPVPTRFIF VLLGPMGGIS
GFHEIGRAMA TLMSDEVFHD VAYKAKNRNH LLAGIDEFLD AVTVLPPGEW DPAIRIEPPA
AIPSQEVRKR PKEEKPKEEF DEEADEQKLR EESGLSRTGR LFGGLINDIK RKGPFYFYDF
KDALALQCVA SFIFLYFACL SPIITFGGLL SEATGKNMAA MESLVSGFVC GIGYGFFSGQ
PLTILGSTGP VLVFETIVYE FCKKVDWSYM SFRFWIGTWI SIILMILVAL DASACVCYIT
RFTEENFATL IAFIFIYKAI ENVLSIGKKY PLNTYSSETM DYDCWCKPPN TSLPSSYNSM
NWTMLDKTTC ENYNGSMVGD GCNIPHYVPD VFLMSIILFM GTFLLSIELK DFKNALFFPS
KVRQVVSDFA VIIAIFSMST LDHFVGIPTP KLEVPTEFKP TLEGRGWIIW PFQGNPWWSA
IGAFLPALLG TILIFMDQQI TAVIVNRKEN KLKKGCGYHL DLFVLSILIE ICSVMGLPWF
VAATVLSINH VNSLKLESEC AAPGEKPQFL GVREQRVTHI LIFLMIGCSV LLTPMLRNIP
MPVLFGVFLY MGVASLKGLQ FFDRILIMLM PVKYQPDYMF LRQVPLKRVH MFTAIQLACL
ACLWLIKSFS HTSILFPLML VVMIGIRKSL DLMFTQRELK ILDDIMPETT KKHADDLRKL
ENGEEHNEMG YGPPAGNIQI SLANGNIMKI PLASINISEE VNKTGIWQQV NEGNEKTKQS
KSLINVGKQK KHPKKDNSLI ADETTRLTTM TEEDEDDSGI SIKVTHVDLI RSKESISPLK
TNGTTSAETS V
//
