ID A0A158NE00_ATTCE Unreviewed; 367 AA.
AC A0A158NE00;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=105618833 {ECO:0000313|EnsemblMetazoa:XP_012055758.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012055758.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012055758.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR EMBL; ADTU01013080; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012055758.1; XM_012200368.1.
DR AlphaFoldDB; A0A158NE00; -.
DR STRING; 12957.A0A158NE00; -.
DR EnsemblMetazoa; XM_012200368.1; XP_012055758.1; LOC105618833.
DR GeneID; 105618833; -.
DR KEGG; acep:105618833; -.
DR eggNOG; KOG3913; Eukaryota.
DR InParanoid; A0A158NE00; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19337; Wnt_Wnt5; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF77; PROTEIN WNT-5; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 367 AA; 40890 MW; 5FA603F8E3712DEE CRC64;
MTMRGNGPLV ILRSLMVAAA ATTVPGTWIN LGLRHLPQLE SAQTMELFDA SASTICVGLK
GLSQGQGKLC QLSVDHMFSV AKGAKYGVME CQHQFKDRRW NCSTVHDETV FGPILRIASR
ETAFVHAITA AGVVYSISRS CRDGHLSSCG CSRSNRPKDL KRDWIWGGCG DNLEYGYKFT
QAFVDVRERE RSFKRGSREQ GRSLMNLHNN EAGRRAVVKR SKVTCKCHGV SGSCSLITCW
QQLASFREIG DFLLDKYDGA TEVKVNRRGR LSMRDPRFSV PTANDLVYLD DSPNYCLPND
TLGSLGTQGR LCNRTSSGMD GCNLLCCGRG YNTQKSTIRE RCECKFHWCC FVECKTCVKN
IDIHTCK
//
