ID A0A158NQW3_ATTCE Unreviewed; 2229 AA.
AC A0A158NQW3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN Name=105623131 {ECO:0000313|EnsemblMetazoa:XP_012059921.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012059921.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012059921.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
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DR EMBL; ADTU01023670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01023671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01023672; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01023673; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012059921.1; XM_012204531.1.
DR EnsemblMetazoa; XM_012204531.1; XP_012059921.1; LOC105623131.
DR GeneID; 105623131; -.
DR eggNOG; KOG0518; Eukaryota.
DR OrthoDB; 298396at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21311; CH_dFLNA-like_rpt1; 1.
DR CDD; cd21315; CH_dFLNA-like_rpt2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 20.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR PANTHER; PTHR38537:SF17; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 20.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 20.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 20.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 20.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 35..140
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 156..259
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 266..364
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 366..463
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 464..560
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 560..651
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 654..750
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 751..846
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 847..945
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 946..1038
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1037..1131
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1132..1227
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1240..1323
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1342..1442
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1442..1534
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1532..1623
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1626..1718
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1716..1816
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1819..1911
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1913..2006
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2008..2099
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2135..2229
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2229 AA; 241313 MW; 3ED10868AD6717EF CRC64;
MNENDKSVKC ENSAGEEEED EMFERELAED AQWKRIQQNT FTRWANERLK VANKHIGDLE
CDLSDGLQLV SLIEVLSQKR LPKHNQRPTF RSQKLENVSV ALKFLEDEGI RLVNIDSSDI
VDCKLKLILG LIWTLILHYS ISMPMWEGDD GEDKGATPKQ RLMHWIQSKV PDLPISNFTS
DWNDGRAVGA LVDAVAPGLC PDWRDWNPKD AVQNASEAMG LADDWLNIPQ LIKPEEMVNP
NIDEMSMMTY LSQYPSAKLK SGAPLRARTN PNRVRAYGPG IEPTGSIVGA PANFTVETFS
AGKGNVDVIV DDPKGNKLPV DIRFNKDRNL TYSVSYTPKM EGPHKVKVLF AGREIPKSPY
TVNVEGHAGD PSKVTASGPG LQPEGVVVNR PTFFDIFTKD AGRGVPEVII LDPQGNKTTS
VKLRQTSPDV WRCEYVSPVT GLHSVNIFFA GKPIPRSPIG VNIAPVSDAK KCRAYGRGLL
PTGVRVQDIA DFIVLTKDAG EGVPDIRVIG PGGVSQPVQM SKTDATTYKC HYTPVKEGRH
VVMITYGGRE IPKSPFEVNV GPYKESNIKA FGPGLHTGVV GHPAKFTVNT NGETGALGFS
IEGPSKAKIE CNDNGDGTAD VSYLPTAPGQ YAVHILCDNE DIPKSPYIAT ISPKTDFDPE
KVEVYGPGIQ PEGVAKDEPT NFTIDAREAG QAALEVAIQD ALGKEVPLRL GDNRNGTVQA
YYTPISSSPH VVMVNYGGVA TKKSPYRVKI ASPLNPAMVS AFGPGLEKGV KSNVPTHFNV
DCREAGPGKL DIKMVNPEGR ELPISLTDNE DGTYVVDYMP PQPGNYTVNL NYGGLKVPQC
PIKVNVQPHV DVSKVKVDGL APSLFVNKQT SFTIDTRDIT KSKTDDGKVS CIINNPSGGK
TEKLIIPQGD GTYCVSYTPF EEGCYTIDIL YDNVPIPGSP FSVNVQRASD PSKCRAYGPG
LEQGITDKTN YFTVETKGAG NGGLGVSITG DGEVRAEARE KWDGSCDVEY VAREPGDYEI
DIKFAEQSIP GSPFKIKVIS PKKNVIAYGP GLHMVREGVP AKFTVDASKC DKQAPVKVRM
SPNLGQEPQI KSKGDGLYEV TYQPPPAGSN VRLDVTFDDD NINGSPFDVK VLPFVEPNKV
TLSGPGVAPF CTASFPIDFI VDTSNAGYGD LEVQVVGPDQ VPRKVVVQDL GDGKYKATYL
PDDCGRYKVN VKYGGKEVPN SPVTVQSTSI GSANNCKIKE GIQHTLAQGE EYCITVDTEN
AGRGAVTCRI RSTTGSEVVD IDIEDNGDGT VNIYYTVADA GDYTLSIKFG GQPVPDGFYT
FTASEEYREH STHKTQRARK TRQKQNQHVV EQRSTTLQES STLSKKNFNV IRLNSIPLPL
PSGGTVTSEV KMPSGNVDKP VIEDNHDGTV SIKYEPREEG LHEIYVKFNG EHVQGSPYKF
HVDSLASGYV TAYGPGLVYG VCGEPGNFTI STKGAGAGGL SLAVEGPSKA EISCHDNKDG
TVSVSYLPTA PGEYKITVKF GDKHIRGSPF VAKITGEGRK RNQISVGSSS EVQLPGKVSD
ADIKSLNASI TAPSGLEEPC FLKKMPGSGN MCVSFTPREA GEHIVSVKRM GKHIPNSPFK
IDVKDREVGD AKKVKVSGPG LKEGKTHVEN KFSIDTRNAG FGGLSLSMEG PSKAEIQCKD
NEDGTLNISY KPTEPGYYIM NLKFADHHVE GSPFTVKVSG EGSNRQREKI QRQREAVPIT
EVGNQCKLTF KMPGITSFDL AATVTSPGGV TEDAEIKEAE DGIYAVAFVP KELGVHTVSV
RYKSMHIPGS PFQFTVGPLR DGGAHRVHAG GPGLERGEQG EPCEFNIWTR EAGAGTLAVS
VEGPSKAQID FKDRKDGSCY VSYVVSEPGE YRVGIKFNDQ HIPDSPHKVY ISPAMGDAHK
LEVAQFPESG VQPDKPCTFL VRKNGAKGEL DGKLVSPSGT QDDCFIQSID ADTYSVRFMP
TENGIHQIHL KFNGVHISGS PYRVKVGKVD ADPAALHAYG NGLKEIKTGQ KTDFIIDTCN
AGSGALGVTV DGPSKVAMDC TEVEEGYKVR YTPLVPGDYY ISIKYNGYHI VGSPYKVPCT
GADLAERGAQ ETSSIVVETV QKISKSKQTG PVLPLFKSDA GKVTSKGMGL KKAYLGKQNQ
FTVHAGDAGN NILYVGVYGP KGPCEEVFVK HTGRNNYNVS YLVRERGEYI VIVKWGDDHI
PGSPYKVEV
//
