ID A0A158P485_ATTCE Unreviewed; 1869 AA.
AC A0A158P485;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=105627932 {ECO:0000313|EnsemblMetazoa:XP_012064593.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012064593.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012064593.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
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DR EMBL; ADTU01008722; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012064593.1; XM_012209203.1.
DR STRING; 12957.A0A158P485; -.
DR EnsemblMetazoa; XM_012209203.1; XP_012064593.1; LOC105627932.
DR GeneID; 105627932; -.
DR KEGG; acep:105627932; -.
DR eggNOG; KOG2177; Eukaryota.
DR InParanoid; A0A158P485; -.
DR OrthoDB; 2905462at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd14954; NHL_TRIM71_like; 1.
DR CDD; cd16524; RING-HC_NHL-1-like; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24104; E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED; 1.
DR PANTHER; PTHR24104:SF54; THIN, ISOFORM C; 1.
DR Pfam; PF01436; NHL; 6.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51125; NHL; 6.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 10..52
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 1594..1637
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1641..1684
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1691..1731
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1735..1778
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1782..1825
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1829..1869
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REGION 297..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1178..1259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1284..1309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1352..1583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 201..228
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 323..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..663
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 973..988
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1031
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1181..1206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1217..1248
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1358..1404
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1540..1566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1869 AA; 207278 MW; 8A06CA2406C18AA7 CRC64;
MEQFEQLLTC AICLDRYRNP KLLPCQHSFC MEPCMDGLVD YVRRQVKCPE CRAEHRIPYQ
GVQAFPTNVT LQRFLELHIE ITGELPDPTS GQTMERCGVC SEKSYCQLCV HCEKKCCPEC
KDAHMDILRR EITRINSQVR RGLHRLQDAL ALVEKNTLGL QTNCASVAEE VDEIYRRLSK
ALKDRTEHLR NEVDRYLGTE LRGLIQLKEN LELEIANIQS NCDLAEAHIN ENVPWDDAEL
LDTKELFLRT VEFIRNFEYE AGDYNRRVRF VMAHDPNQLV LHVAGYGELN IKPESGSGGL
LGSSSSLAPP VGSPGLMRSK SDHRLASQYR QQEEERLARN RYVPEYEYDA PEYEVPRNKS
RYRSRFMRHR DGDDSDGDSR STVRFTSAPP ESSSLRERVL DTEDAARGPL SGIFRLTDSP
RVMKKLQECE RAGKRKKEEP ASQPMPQPQP PKPQVQVRKV PTAMARQTSE DDEISRIKKQ
NKNAATTAVH TETVEERQPT SMPPPVHPPP RELPEREPEE QPIRRPTIVR RTSETHASPA
ARSASSDSST GSESSGGSGI RSTGAPFTAE EMKQKYLSRA PPTSTTTTIS TTTGREPSNT
APPTPRPPFQ SRFLGAGNRA APPPPVQTPR EESVAKKKEE EDDEDEETSS SSEETESDTE
EESETEGHPS KTTSTTTSAA SQDRQRSESA MARTDIGPLL ARSAEARRGS KEDSPSTRYS
SPRGSPAQSV TTMTTTMTTP SGGGGAAMTT TSTPGGYTSR AFSADGTDER CSAGRVDDAK
VIAATATVAD SAYDINADGN ALKPQATNTS SAQTDVITDK STTSSTSSYL AISEPENLLG
NSRGDSRVMN VTFEDDDALV QDHSGNGESR SQDELSTITI EDDSNTRRNA TEEMISENHD
FEDAPSFFRI IVEDVDASVA EKSMLDSTNQ SRCEIIDEIE RRDRSRSKES HSISECSSSV
SGRTMSYSES ESDSENVSEE ENEEEDESRD ENCNVKNKKK ENKKDDRNYD DNDNAESEVN
EENKESSNSD SDEETTVLSI SSNIQGESSA TPDDRYERDL KRRSASIIDE RSIEEMFDDN
GWVVTEQDLE QDLPNDLRTI TSSIGDVNDA AGTRTDEIIP KIAEERHNET FSNFEDFSTQ
SSITINAEMV PSSEWQGFEA PSRSRVYRQS SLGKNGWLVS DESESESDRA TSPIEASSDR
DVTRTEFANE AIGFDGIEDT GDIDENGWVI LDDDDDDDDD DNNNDELDEE LTGASSAQEN
TICSQTIDFV DSKTNIENGA LVADVKRSKG AEQSGPDKHE ETSGASMSVP MQMDVSRICD
KKCGTSVVPD SCTHPWSWNR IRSVAASFLN KSRSQAAMMA SRERERERDR ERERERERER
ERERERERDR ERERERDVDA EIDSPLSTRS RYAALKERRQ RLARSRSSHN FGGDDLDLDE
EPPSPTTQSP NAYLAAKYGA GSELARSRST HALKSREPSP ERDRPGTEKD SAALSSWARY
LKNKYGNRTT KDKESPSSSS TIPSSSTSAA SRRLSLGLPL RHTGQTSFES SDDDQKNPSG
SPTSPTAAPV IPAAAGSSTS NGRRSHYLLK RRQLFKFGMR GSEAGCFTWP RGLAVGPDNS
IVVADSSNHR VQVFDGNGNF MKEFGTYGSN EGEFDCLAGV AVNRIGQYII ADRYNHRIQV
LDPSGRFLRA FGSQGTADGR FNYPWGITTD ALGFIYVCDK ENHRVQVFQS DGTFVGKFGS
CGSGRGQLEH PHYIAVSNTN RVIVSDGNNH RVQIFDVNGR VLTSFGSEGS DEGQFKFPRG
VAVDDQGYII VADSGNNRIQ IFSPDGAFLK SFGCWGSGDG EFKGLEGVAV TSTGNIVVCD
RENHRVQVF
//
