ID A0A158P542_TETUR Unreviewed; 877 AA.
AC A0A158P542;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur13g04926.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur13g04926.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
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DR EMBL; CAEY01000163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A158P542; -.
DR STRING; 32264.A0A158P542; -.
DR EnsemblMetazoa; tetur13g04926.1; tetur13g04926.1; tetur13g04926.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 583..762
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 194..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..459
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 877 AA; 99911 MW; 15F175E8CC63C5EC CRC64;
MIADLCPADY RSYLSQELYK SKQKIGQSAI AFIYEIHELC RRIHEQTPEV FIISMIKEKL
LPQIKYGIAL QNPKTLHELV EAARLAERAM HSCSTPFDAP SKEVTQLQTQ VQQMKEKLES
LKRCNICKRL GHTEERCYFA KRPENEIRQN NYGNRNQGLN NYPATSHNPN MAQYNQDYQR
VISQANQNYQ TAARNFIPGN PGVSNQTFAK RTFPRNNADP DNWRNRPSIS IKEPEVKMDP
PKGSEYKSKT KERSPSPKRR GRPPSKDRGR GRGRGKAPQV RITTYRDDKS EEEVDSDYCI
ESDEATFVNP VVHLLNQNLI QQFVKVNGCK VDSMLDTGSE ISLITKDLVH ELNLNVSKYK
GPTPFAANNK PLPILGKVKV QLKITDGRKI AIIDTKMQVV YNLPRKFKVL IGQDLLTRAQ
VNIDCANRKI KIGRVEPVVE IVTTEEESSD SEPTVDTSTE SEDLNDLLND LNDFVSSDVD
QLPELTEDVE LEIEPITTFV DKSKIPELEL NIEKDVPGGV EQALYQLCNN YREVFAVTPQ
ELGRTNLFMH RIETGHHAPI SQSPYSQSAQ KREITKQIIN ELLRDGIIVD SFSPWCSPVV
LVSKKTGDWR MCVDYRKLNA ITVKDSYPIP NINVSLDALQ GSEYFSLLDL RSGYHQVELA
PEDRQKSAFV TSFGMYEYVT MPFGLCNAPA TFQRLMNCCL GGLKYKCCLV YIDDIIVFSK
TIKEHLERLE AVFDSLRRAG LTLKPDKCFF FKKKILYLGH IISAAGQEPD PEKIRAVKNF
PVPITLKDIR AFVALCSYYR KFIKDFAKIA QPLTQLTKKE VPFIWGPTQI EAFEYLKNCL
VKAPVLAHYN HMLETQLRTD ASDVGLGAIL LQKHENK
//
