ID A0A158PK08_ANGCS Unreviewed; 741 AA.
AC A0A158PK08;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=NAB co-repressor domain-containing protein {ECO:0000313|WBParaSite:ACOC_0000945801-mRNA-1};
GN ORFNames=ACOC_LOCUS9459 {ECO:0000313|EMBL:VDM61044.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000945801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0000945801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM61044.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM61044.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NAB family. {ECO:0000256|ARBA:ARBA00008864}.
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DR EMBL; UYYA01004300; VDM61044.1; -; Genomic_DNA.
DR STRING; 334426.A0A158PK08; -.
DR WBParaSite; ACOC_0000945801-mRNA-1; ACOC_0000945801-mRNA-1; ACOC_0000945801.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.120.2010; NAB conserved domain 2; 1.
DR InterPro; IPR006989; NAB_co-repressor_dom.
DR InterPro; IPR039040; NAB_fam.
DR InterPro; IPR006988; Nab_N.
DR InterPro; IPR038398; NCD2_sf.
DR PANTHER; PTHR12623; NGFI-A BINDING PROTEIN; 1.
DR PANTHER; PTHR12623:SF10; NGFI-A-BINDING PROTEIN HOMOLOG; 1.
DR Pfam; PF04904; NCD1; 1.
DR Pfam; PF04905; NCD2; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 95..124
FT /note="Nab N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04904"
FT DOMAIN 362..438
FT /note="NAB co-repressor"
FT /evidence="ECO:0000259|Pfam:PF04905"
FT DOMAIN 454..502
FT /note="NAB co-repressor"
FT /evidence="ECO:0000259|Pfam:PF04905"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..563
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 80592 MW; 54F50FFAE2B666D5 CRC64;
MSSSDGNNTP SPSSVASSSQ QQPLDKEYEE MNGFYGGVFI RYDLVSGLLL SALPTSSSSQ
LQIPAVTKNS MKRESPQLKA EGIVRTSTPK TLTPPTSISE WQLLAVLQRA NLVQYYDMFI
SQGKNNETCK KPITSVTTNS SKCLGVTYLM HDGSCPKRNT YVHSNAGGLM KLAIVARASR
LMPSSQRQLV EFSKDQTTFN LAAIQHIGPP PVSPYALGGP DMSFLMPGFA ATLTNLSSTS
PGLTATSTEN TSPQNGNVTH NSVPLAIELS AAVLGTMATS VTINNRSCVG DFSAGSAPIP
PAAPGGTANV VRGEFLPAFG QGSINVTGEE KERSSSPLSI GGDFVSLGDY DPNTALCDSP
VLSDAQIRRL STCAMAICQK IPRLPPKLVQ NKKRVSKEVL DLLSASADAP NRLADYRKYS
AIYGRFDAKR KPDKTDTLVA ASMKYTDDFV LHGLSFHEVS VNEAAAQLCL IMPSLLTRRD
ELFPLARQVV KDAGYHYAKA SRKRGLDHID SHSPQSSPTY SPCLGDDNDV DVDSVFGSST
VKQSDEKRKK SDTDGEEDRN SQTSYRIMRK FPKSFQKWLN ASGTHSGCFL NEWEGKKWME
KPHKAVTESA MQVIAYAHLG STIRQCSCAE DRECVKSMEE QYYRPCNAIT NVGLSSPSCV
KTERGPQIPQ VDLRRLFTIG EQQLNATSAE VLNSDLIANI RCQPLITKNN LRSALRSCLA
TIDWKQSIAD LCHCAQDVGF R
//
