ID   A0A158PKH4_ANGCS        Unreviewed;       436 AA.
AC   A0A158PKH4;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};
GN   ORFNames=ACOC_LOCUS10092 {ECO:0000313|EMBL:VDM61677.1};
OS   Angiostrongylus costaricensis (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC   Angiostrongylus.
OX   NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001009101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ACOC_0001009101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM61677.1, ECO:0000313|Proteomes:UP000267027}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Costa Rica {ECO:0000313|EMBL:VDM61677.1,
RC   ECO:0000313|Proteomes:UP000267027};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sodium-phosphate symporter. {ECO:0000256|RuleBase:RU363058}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 Na(+)(out) + phosphate(out) = 2 Na(+)(in) + phosphate(in);
CC         Xref=Rhea:RHEA:71259, ChEBI:CHEBI:29101, ChEBI:CHEBI:43474;
CC         Evidence={ECO:0000256|ARBA:ARBA00035083};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU363058}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363058}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000256|ARBA:ARBA00009916,
CC       ECO:0000256|RuleBase:RU363058}.
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DR   EMBL; UYYA01004408; VDM61677.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158PKH4; -.
DR   WBParaSite; ACOC_0001009101-mRNA-1; ACOC_0001009101-mRNA-1; ACOC_0001009101.
DR   OMA; ITWVGYK; -.
DR   Proteomes; UP000050601; Unplaced.
DR   Proteomes; UP000267027; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PHOSPHATE TRANSPORTER; 1.
DR   PANTHER; PTHR11101:SF80; SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363058};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW   ECO:0000256|RuleBase:RU363058};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363058}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        93..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        140..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        175..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        205..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        331..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        370..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
SQ   SEQUENCE   436 AA;  46737 MW;  F86D40D4F6491ADC CRC64;
     MTGDLAAFQS ALLPWLIVGA VIAFILAFAI GANDTANSFG TSVGSKVVTL TQAYILASIF
     ETLGACLLGD KVTDTMRKGV LDLSVYNNSE GELIYGQISI LSGCGAWMLL ATFFKLPVST
     THSIVGATIG FSLILKVGSW VISPLLSGLV SVIFFVFIDH IILRRSNPLN SGLKILPVLY
     FLCMTFNVFA IIYEGSEYLY FNHLTLKHCA IISCLFGVVS AILAKFVIAP WLKRNILARS
     NLESNSLNEL KVANGQTTTL LEIQSETPIR EKEARAVSSS GHALNTIAPS SSIASFFRSS
     KPEDPQTALL FSLLQVMTAC FGGFAHGGND VRYILLYGAV GMCIGLWLLG HRVIYTVGEN
     LTKITPPSGF AIEFGAAVTV LLASKLGLPI SSTQCKVGSV VAVGLVQASH SVRWHTFRNI
     SLSWIVTLPV AGEVES
//