ID A0A158PKI0_ANGCS Unreviewed; 709 AA.
AC A0A158PKI0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Venom dipeptidyl peptidase 4 {ECO:0000313|WBParaSite:ACOC_0001010601-mRNA-1};
GN ORFNames=ACOC_LOCUS10107 {ECO:0000313|EMBL:VDM61692.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001010601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0001010601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM61692.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM61692.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
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DR EMBL; UYYA01004411; VDM61692.1; -; Genomic_DNA.
DR STRING; 334426.A0A158PKI0; -.
DR WBParaSite; ACOC_0001010601-mRNA-1; ACOC_0001010601-mRNA-1; ACOC_0001010601.
DR OMA; MRTPQEN; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF200; DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 39..415
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 507..702
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 709 AA; 80785 MW; 941AF1491B134024 CRC64;
MLVTGEREHL SSSTVTLVQP GTFDAVEYPM DASLVRAMSS NRKYAYITQN TKEIFRHSNE
ELYEVFRIVN GTRTGDSFAV GPKGNGFEAI HSLEWNPNPN KNDFIFVHDY NIYYQDDPEK
PGSAVKLTPD GNYLLRYGVP DWLYEEEILL SGDAIWWADS GDYVAYLRFD DRLVNRIYIP
EYFRGSQYPQ YIEIPYPKAG VKENPLITLY IWKVSTKKSV IIEPPLALMK MNQSYYVFTS
KWLKMPIDVR RSFGFERLLT VWATREQNLL YITLCNDTDC LLTYTQSFTI NGQSMWAEPS
DFKQILASRV GFFVILPHAY HDGNIYNHIA HIQILKNGSG RITSWHGESY DIHEIKAYNM
KSDTLTFTSA GGAIGTMQLY KSSVISLSSF ILDCDYGSFD VSPDGRRVAA SCLQPFRNTK
MYLMDIDIPS NNKLLEGADE THIPFDLPEL SFELMELPSN YGESDFKAHV GIMKPPMFDP
TMKYPLLVDV YGGPNSCRVR RVTPNSNMIY FCSHLNAIVV WIDGRGASNR GWNLKSPVYK
ALGQYETQDT IDAVKLLISK YSFIDEQRVA IFGWSYGGFV STYAGILDQG KTFKCAIAVA
PVSNFMLYDS AYTERYLGVP LENPTGYNAT QLLNKAGLLK NVKYMLAHGE ADDNVHFQNS
ALLSEKLQAE LVHFTQLVYS NQDHNIGTRQ AHLFMEIDRF LTNECFNDI
//
