ID A0A158PKW6_ANGCS Unreviewed; 594 AA.
AC A0A158PKW6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Transmembrane and coiled-coil domain-containing protein 4 {ECO:0000313|WBParaSite:ACOC_0001062901-mRNA-1};
GN ORFNames=ACOC_LOCUS10630 {ECO:0000313|EMBL:VDM62215.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001062901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0001062901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM62215.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM62215.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
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DR EMBL; UYYA01004511; VDM62215.1; -; Genomic_DNA.
DR STRING; 334426.A0A158PKW6; -.
DR WBParaSite; ACOC_0001062901-mRNA-1; ACOC_0001062901-mRNA-1; ACOC_0001062901.
DR OMA; NSWRIAF; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 236..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 35..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..579
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 63980 MW; 3580A43F41650ACF CRC64;
MRVACIVDVQ RHAIAGLPLN KNPAFLQRTV SMDTPESTTP SLIQEGFPAR PSSASDLTSE
TSPNTILTSV AATTFEATTR FAITELTACV LHLDFWDEDE PNSIFFSKMT YDIVVSHLQI
PEKVARTVKT HLEGEENIPD IATLITTIKD DRLVKENGTI VVLSSLVVAF INSGNYDARY
RVLLRHIATL LSVVWEEFED IEDSLTSTML DEVYVESEQA KQIREKTQRK KKIKRFLLVG
AAGGVGGVLI GLTGGLAAPL VAAGAGVLIG SGAAGLATTA GAAVLGTTFG MAGAGLAGYK
MNKRVGAIEE FAVEALSDGL SLHCTLVVSG WIEEDTPCDE AFERQWKQLN MSREQYTLRY
ESKYLKELGK AMDYIMSFAV SVAIQQTLME TALAGLLAAV AWPVTILSAA SVLDNPWSVG
EHLAEVLLGR SHGKRPISLI GFSLGARVIY HCLLAMNKRA ESAGIIEDVI LLGAPVSASP
KQWSQLCSVV GGRIINGFLY RTMCVQFTIA GTGPVKGHLD YSRKLTEVLA AVGVRVKELP
TTEISDEIVR ETGDEGQDAL TSRPSVRDGG HKDCLPAESN KVAETAVRDK LDIG
//
