ID A0A158PRU8_BRUPA Unreviewed; 1022 AA.
AC A0A158PRU8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Adhesion G protein-coupled receptor A3 {ECO:0000313|WBParaSite:BPAG_0001126001-mRNA-1};
GN ORFNames=BPAG_LOCUS11222 {ECO:0000313|EMBL:VDN92408.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0001126001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0001126001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN92408.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UZAD01013219; VDN92408.1; -; Genomic_DNA.
DR STRING; 6280.A0A158PRU8; -.
DR WBParaSite; BPAG_0001126001-mRNA-1; BPAG_0001126001-mRNA-1; BPAG_0001126001.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45930; G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN; 1.
DR PANTHER; PTHR45930:SF4; G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00369; LRR_TYP; 3.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1022
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041044425"
FT TRANSMEM 702..727
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 798..819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 839..866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 912..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 948..966
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 235..330
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 313..395
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 737..969
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 1022 AA; 115919 MW; 5E079FEC8F5FFEAD CRC64;
MKRFNKFTCL FAICAFELTV LIHCNWTRCS YLVDTAIVDC SGLNLDKIAQ TAQLKASTSE
FYPSTIGGQV YLLNLSGNAF RSINSSSFSS LRHPETLEIL DISHNAVMFI SPGAFKTLSN
LKILLLNDNQ LHALDRLSFV ELESLEELDL DSNPLSSFPD GTFASLSKLR KISIMSNQLS
CDCQIVDLLR LIKDHQVQVS NRTVCIFPHS LRGMQVAGLN AKALKRSCGK GNFNPAVFDL
EPTTRSIVVY PGDEKNVTCK VSKANDVRME WLKNNVPLVD SSRLFTTHYN DSEFLYLKLC
LNPVTWEDEG DWTCYVEQDR SALRNTVRMT PVLVNTVHCV QEWQADEKGE IIWAVSKQGL
VTAKCPNGPT NAKAYRRCKH GKWETPDTSR CAYTSPLIKY FLTLLQHKRT SQYMDELLRI
TRRPFEMSAY ETRLVGWLIG NATGLSSRQM LAALNFVLQS EFARTELNGK LMRQHLQHLL
LGDKVIQEDN LAICQHLFAK GYDGTPAEIM KGGFLTLHDG SKFSCREQQF VELLPKTGGA
SLRIPRHTID HFPSLTIVRV LWLSNSKIFE SKHTSDGRWT VMSEVYGVAM KHIPIRSSKS
SNIVDEAAEV RKNDDFYGFL INYQTNKTAN EIQLGVWDDE EGWKLTKETN CLLRKVEPNN
ILFTCSRMFF IKNVDENIKY FAAMQNTSYE ELIISARKPM KLTWYICASS GFLASIMLLT
CILHSFIHNE IFDPHTCRAV IIVQYFFFLA VYFWIMQAFR LLQEKLRRIV RDYSRSKSDE
KVHAEVEKVA LYGAIMEMYF IAYGIPLIAM STVLATGTLP HDGSPKFYFH SSKMHSEVFA
YAVYAPLLIC SILIMAIIVV ILRLLITAKR ISVESISQQY VDNKSSKENT QIRNATASAE
LNKMANAATI QLLWLLLIAV LYSSDCYAAT SYINHLNDLE PSATPKSYFN ALLNILLALA
IFYLFTFEWI RTITLKACDS SCSTCVTKQL ISLPYSYQER VMPPVQQIGS IAGCFVEGGE
WV
//
