ID   A0A158PSY0_9BILA        Unreviewed;       805 AA.
AC   A0A158PSY0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Discoidin domain-containing receptor 2 {ECO:0000313|WBParaSite:BTMF_0000798901-mRNA-1};
GN   ORFNames=BTMF_LOCUS6088 {ECO:0000313|EMBL:VDO20833.1};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000798901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BTMF_0000798901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO20833.1, ECO:0000313|Proteomes:UP000280834}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; UZAG01015492; VDO20833.1; -; Genomic_DNA.
DR   STRING; 42155.A0A158PSY0; -.
DR   WBParaSite; BTMF_0000798901-mRNA-1; BTMF_0000798901-mRNA-1; BTMF_0000798901.
DR   Proteomes; UP000050602; Unplaced.
DR   Proteomes; UP000280834; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   CDD; cd00057; FA58C; 1.
DR   Gene3D; 2.60.120.1190; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR048525; DDR1-2_DS-like.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   PANTHER; PTHR24416:SF600; PDGF-AND VEGF-RECEPTOR RELATED, ISOFORM J; 1.
DR   PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR   Pfam; PF21114; DDR1-2_DS-like; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR   SMART; SM00231; FA58C; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS01285; FA58C_1; 1.
DR   PROSITE; PS01286; FA58C_2; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        366..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..151
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   DOMAIN          534..791
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   805 AA;  92704 MW;  B4E92433C1974359 CRC64;
     MESGLIKDNQ LSASSSHDKD TTGPQNSRIR TERGSGAWCP RQQINSETVE WLQIDFDMDM
     VITAVETQGR FDGGRGLEYA PSYMLEYWRE SLGTWARYKD GKQNEVMAGN SDTQSTVFRA
     LDGGVVARNL RVIPVSEVTR TVCMRIELYG CSYRDQILSY VIPEGDIIDG LNLRDISYDG
     ITNSSGYLVK GLGKLYDGAV GMDNFESYPE KWIGWNREKR GATITIEVLF AKKKIINAIL
     FHVSNFLKSG AQVFKRAHVW FSSQGGGQYS PRTLHFNYIP DKNFQSARWV RIPVPSRIAK
     ELRVELTFSK NSTWLLLSEI KFEFTNEMFK SDDMDDEEFD LDHPSNRGDT LTYFAINDAS
     EDGTRWISIA VIISLLFLFC ALIILFYLLW IYRRAFSRKG PFIVLKKNSK DVRMAVEKQT
     IKRTSPNAYC MTNDNMQNSL LEKLHANQSS GSEYAEPNYI SNDMEIIGVN NTTICDPTKS
     LTNSTIHYAS NDVCMRHPRQ LGYALMENSM TSQIASGYDT NRSTNFVEID SKCLRFHEHL
     GNSRFGEIWL CQLEQRTMVN KTFHRSRDNR REFEIIVGEL SSLRHQNILE VIGVCFDGVL
     TSCIHEYIEQ YLDQYLRSLN NEISYRTELL LSVSTQIAAG MSYLESKNFI HGNLSASNCM
     VANDGTVKLT NFNMAYTLDH LETDDPIDRG RMRWMSWEAV AEKKITIKGD VWSFGVTLWE
     VLNGCHKYPY KMMTDNDVYR NLLFMRQNGM LKFYLERPDF SSVNFYQEFI LPCWNGNSEE
     RPTFHSLHRR LQNVTCAQMS EDCYY
//