ID A0A158Q3R5_DRAME Unreviewed; 916 AA.
AC A0A158Q3R5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DRBM domain-containing protein {ECO:0000313|WBParaSite:DME_0000301201-mRNA-1};
GN ORFNames=DME_LOCUS7171 {ECO:0000313|EMBL:VDN57198.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000301201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000301201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN57198.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYG01001159; VDN57198.1; -; Genomic_DNA.
DR STRING; 318479.A0A158Q3R5; -.
DR WBParaSite; DME_0000301201-mRNA-1; DME_0000301201-mRNA-1; DME_0000301201.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd00048; DSRM_SF; 2.
DR Gene3D; 3.30.160.20; -; 2.
DR InterPro; IPR002466; A_deamin.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR10910:SF144; A TO I EDITASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR Pfam; PF02137; A_deamin; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00552; ADEAMc; 1.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR PROSITE; PS50137; DS_RBD; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 176..239
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 482..556
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 624..910
FT /note="A to I editase"
FT /evidence="ECO:0000259|PROSITE:PS50141"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 916 AA; 101132 MW; 503FC3905998BD9F CRC64;
MFGFAPGWSK SVPTNAQTTG MQRATVRANA APPQKTVAAN ANAYLGSQVK YKPLSTANIN
HSRETANQNL SAMTGAASGY YDCDYSMNYG YYNNHFAGYV PLTSTATSSS TTNTINYTLY
GRGIANSNSE AGFQSSAFPS LLRGTFPRKG RTVSKTNRDG GPASKKQKHY TTAGKSAAMI
LNELFPAFRD NCSYDSVGGV VPRFKCSVTV NYQTFSAEAS SKKVAKQLAC ERALKSLRPD
VVLDVPSYEQ TEASKLATIE ARTGNGSAKD IKRLELLKTS NSLHDYFLKL CRNREAETGI
KYNPVFSFSE IPGAENAKAH MKRFRCTLTM SEQKKVYTNE NIGKTAGKNC IIRERITSNF
IFQALMDIFE VSDTEMNEII RQSLNLRYGK PKQVLLQALS FFGRSMQIKV DSCSTTPAKG
TNPQYMAMIS LDNDNRIFIG PAETSIAEAK NSAYLRVIEE LGFHMPAEEE DIPLKKTSSV
LSPCYALHHL MLKQNQNEPP NIVYADPESI GTNQSKQPLF KCKLTVNNSY LFEGVGLSKK
VAKNAAADQA LKQIFNFDMS SSDAYETLIS KCNKNDDELK LCCDISKLVH SEYDSICLQQ
ACPKTSHISA FVLISPTGER MMVALGAGRN AIVDGHILAN SPGNVLIHMQ SVVLARRALL
IYLHKQIERS SAPKSILEKS SISSKFRLKQ GYKLVLFMAF PPNALPSGSD KQKLSCYTGG
GHIETCNQQQ TFEVMCAAGV SVMSIADKIL KWNIVGLQGA LLSHIMEPIF INKVCIGAPS
SEKAVKNAIL SRYGGIKKAG FSVKALHENI HPHGEIYHNW VAGIGTIERL DPLSCRSVTG
SPSRLCKFEL FESWSRLLNV CGVNWKPMWT YMHAKKGANE YMANLELFYK KLENLKLGSW
QRKDPIIDNF TLISSQ
//
