ID A0A158Q3V2_DRAME Unreviewed; 612 AA.
AC A0A158Q3V2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=PRP18 homolog {ECO:0000256|ARBA:ARBA00031388};
GN ORFNames=DME_LOCUS7406 {ECO:0000313|EMBL:VDN57433.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000324701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000324701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN57433.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYG01001160; VDN57433.1; -; Genomic_DNA.
DR STRING; 318479.A0A158Q3V2; -.
DR WBParaSite; DME_0000324701-mRNA-1; DME_0000324701-mRNA-1; DME_0000324701.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0042811; P:pheromone biosynthetic process; IEA:UniProt.
DR GO; GO:0008380; P:RNA splicing; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR InterPro; IPR004098; Prp18.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR Pfam; PF02840; Prp18; 1.
DR Pfam; PF08799; PRP4; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SMART; SM00500; SFM; 1.
DR SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR SUPFAM; SSF158230; PRP4-like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 4: Predicted;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT DOMAIN 86..136
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
SQ SEQUENCE 612 AA; 71753 MW; 46325348E54AF9C8 CRC64;
MEIITAEIER KRKQIKDIEH VEPSGMKYIK RSDLSAKQEE EYWKRYLSNF FQQSLKKFGY
NFKSIDGTIS KTNSNQKENE FDVDDMPWSE IVKRLRGRSQ PILLFGETRK DSRLRLRKLE
IEQPDMKEGW KNDFQSAMRE VDHELIEEVI KGQQDNAGRH DVDMPNSAGD TSWERIEANA
RLLGEGENPN RDCDIIREFF SYILTRWGKA LNARDEATKR HGCASDFLSF LLIHKLKSAE
GKLAATMHKQ TMEHLRPLMS NLEKHNVNAD IREHLIKICR LLIIDRDYIR ANNAYMEMAI
GNAPWPVGVT RSGLHQRPGS AKAYVSNIAH VLNDETQRKY IQAIINEFQA FKRLMTRCQK
FFQLLKFFRN QIEKFFEEKM ENDEDIDEVH LCAPYNYIRK MPGKGIRNQM TKAFNLWLNI
DEQIMNNILS IIELLHNASL MVDDIEDGTV LRRGLPVTHS IYGVPRTINT ANYMYFVALS
KCLKLNNFEA VDLFTHYIQE LHRGQGKEIY WRDTPHCPTE KEYEKMVLQK TGSLFHLPIR
LMQLFSGRSY DFTSLIHHIS LYFQIRDDYI NLCSKEYEAQ KGFAEDLTEG KFSFLIIAAV
SRDNRDDEIL SK
//
