ID A0A158Q643_DRAME Unreviewed; 552 AA.
AC A0A158Q643;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=SAP domain-containing protein {ECO:0000313|WBParaSite:DME_0000904501-mRNA-1};
GN ORFNames=DME_LOCUS2835 {ECO:0000313|EMBL:VDN52862.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000904501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000904501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN52862.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYG01000083; VDN52862.1; -; Genomic_DNA.
DR STRING; 318479.A0A158Q643; -.
DR WBParaSite; DME_0000904501-mRNA-1; DME_0000904501-mRNA-1; DME_0000904501.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039133; RNF25.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13198:SF4; E3 UBIQUITIN-PROTEIN LIGASE RNF25; 1.
DR PANTHER; PTHR13198; RING FINGER PROTEIN 25; 1.
DR Pfam; PF05773; RWD; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00591; RWD; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..65
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 292..405
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 413..477
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 552 AA; 63216 MW; FC1F7D29064F608D CRC64;
MKQKENCKDL TSFDVASMRL EETKMSSTSN LAKLSVVQLR AKLKSRGLST SGTKIELIER
LNESILVEEK ILNSDESGKD ITDEEAVLND STSVNEDEVL GLTGPMIADI EVENSVLETK
KGSESISEEV SKSKKNLDDE TIDAKMKRAL RFGLPFSSEQ LKQKRAERLF FIHVHYFCLF
ISIYFLLSFH IEIFRFGLKD QLSPEEKKRS RAERFGITNI SSVGNLETTK EILEKRAARF
GLPIQKGGNS KFLVEPPSAE VLAKRAKRFG VSSEKAEISF GNFLHGDMEI NCEIDVLRSI
FGDELLVKKE MSNESNITIL QMIVKGVGID ELENVGPSAT LLVDIIIHPE YPEKSPEVRL
LQPRRIDEKH LRILESNICE LLKDYRGTAV LYSIFQMVKD YITDRNVSPS VLCPICLNGF
EEKSSAIFST FCDHDIHSYC FFKYVDYCRR DIARQLKDWP VDMGHKVDQR IKCPVCRLEL
PKNDLMAAEK FVDVSDDPFK KCDDNYTFDW EKWREFREKL NVIYEKQRLN GGLIESGITR
RHRVISGENL IQ
//
