ID   A0A158Q6J3_DRAME        Unreviewed;       546 AA.
AC   A0A158Q6J3;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Glu_syn_central domain-containing protein {ECO:0000313|WBParaSite:DME_0001025001-mRNA-1};
GN   ORFNames=DME_LOCUS3751 {ECO:0000313|EMBL:VDN53778.1};
OS   Dracunculus medinensis (Guinea worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX   NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0001025001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:DME_0001025001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN53778.1, ECO:0000313|Proteomes:UP000274756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glutamate synthase family.
CC       {ECO:0000256|ARBA:ARBA00009716}.
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DR   EMBL; UYYG01000179; VDN53778.1; -; Genomic_DNA.
DR   STRING; 318479.A0A158Q6J3; -.
DR   WBParaSite; DME_0001025001-mRNA-1; DME_0001025001-mRNA-1; DME_0001025001.
DR   Proteomes; UP000038040; Unplaced.
DR   Proteomes; UP000274756; Unassembled WGS sequence.
DR   GO; GO:0015930; F:glutamate synthase activity; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 2.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006982; Glu_synth_centr_N.
DR   InterPro; IPR002932; Glu_synthdom.
DR   PANTHER; PTHR11938; FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR11938:SF133; GLUTAMATE SYNTHASE (NADH); 1.
DR   Pfam; PF04898; Glu_syn_central; 1.
DR   Pfam; PF01645; Glu_synthase; 1.
DR   SUPFAM; SSF51395; FMN-linked oxidoreductases; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000274756}.
FT   DOMAIN          87..371
FT                   /note="Glutamate synthase central-N"
FT                   /evidence="ECO:0000259|Pfam:PF04898"
FT   DOMAIN          465..533
FT                   /note="Glutamate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01645"
SQ   SEQUENCE   546 AA;  62207 MW;  D574D26E417B811C CRC64;
     MLLIDLYEKK LIDDDDLKLK IASLRPYKKL CSKRIHLNQL RELHVLATGA ITHESLITRE
     LSKQSIPAYR LNKAQREKDY HLDSDRRLTA FLYTPDTFAL IIAPMVLQQK EALGSMGNDA
     ALACISDYSP LLFYYFQQLF AQVTNPPIDP FREQIVMSLR CPIGPEPNIL EPNEEIVPRL
     MLEQPVLSLI DLEVLKQTTV ANWRSKVIDI VYPVRHGPKG LVPSLDRICS EACAAALDDY
     QLIILSDRKI DKDFVPISSL LALGAVHQCL LKQKLRVKVA IIIESGEVKE IHDFCVLLGF
     GADAICPYLV YETCHRLRNL GLIDDTLTDA KIYQGYTAAI ERGIFKVMAK MGISTLHSYK
     GAQIFEAVGL SQEVVDRCFT NTISRLGGAT FDILATESLK RHRNAYPAVE EKYNYGLFFN
     FSFNFFCSFL KIYLLMINFR IIGDSKTLIS HGTYHWRDGG ERHINEPFNI AKLQAAVRLN
     DKRSYQEFSA ASNMAQRLCT IRGQLEIKTS RNLQIPLSEV EEASNIVKRF VTGLYFSLLL
     FFYRKK
//