ID   A0A158Q9N2_ENTVE        Unreviewed;       901 AA.
AC   A0A158Q9N2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000258601-mRNA-1};
GN   ORFNames=EVEC_LOCUS2294 {ECO:0000313|EMBL:VDD87151.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000258601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000258601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD87151.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC       {ECO:0000256|ARBA:ARBA00007242}.
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DR   EMBL; UXUI01007353; VDD87151.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158Q9N2; -.
DR   STRING; 51028.A0A158Q9N2; -.
DR   WBParaSite; EVEC_0000258601-mRNA-1; EVEC_0000258601-mRNA-1; EVEC_0000258601.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24060:SF171; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR00593; MTABOTROPICR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..901
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033250903"
FT   TRANSMEM        511..538
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        550..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        576..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        617..643
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        666..688
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        700..723
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        735..759
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          512..774
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   REGION          810..831
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   901 AA;  99380 MW;  E7EAA407C213AFAA CRC64;
     MQVEYIVFIV LILTIDSHAV IAIKQVKVDG DILIGGLFPV HEAGRHGEEC GVLKPDQGVQ
     RLQAISDDSH ALKQTFVFIK AMLTSGDEIV CPDGGRPIMG NQSVALVIGA ASSQVSVMVA
     SMLQLLKVPQ VSYSSTGAEL SEKSRFQYFS RVVPPDDLQA DTLARLVKRL NWTYVHAIAV
     TGSYGERGMD SFRAAADVEG ICIDGSRMRN TNKARGVVMF VDEDNLRRIL YNLDYIIQRN
     STFVASDSWG TKRSVPSGYE AITKGAITVA PDRNQTPGYN EYFLNLSPGD NVFLQEYWEY
     LNCSVQNANF RECFKQRRLK FNQEAYVSSV VTAIKLVANA LHKYILKFCG GFDNFGDCEV
     SKIGFNGTIL QSYYRNVSLS NKPKDPPVID ANGDGLGRYG IYQLDSKGVY QKVGFCHAGK
     PMNLDIKRIR KITQSRGGMP KSVCSLPCGR NRYKEYNQDQ RCCWTCIPCD PATSIVINET
     KCVECPAIEV PNQFYNACKP IKPEVFEFNS LWVLIPSSFS VLGILATSFV IAVFMRYSQT
     PVVKASGREL CYCMLFGIGL CYCVTFILLS KPTPNICALS RIIIGLSMSV VYAAILTKTN
     RLSRVFSPKS AARPGCIVPR AQIAICAAIV SVQVVGSLIW LVWEPPGITI QQPTRTTAVL
     TCKATAAHLV ASLLYNMLLI IACTIYAFKT RKIPENFNET RLIGFTMYST SILWLSFGPI
     YFATQNNFKI QITSLSMAVS LSGTVALCCF FAPKVYIVIW QPDKNVRTRQ SAVGRLVNQQ
     MRFISQITAP ATANETSLLT ATENYSTPQV TQFSSDPEVT STSSIQASQA SRSPATIKTA
     ILSTSNNGSI VNEPIGLPKS QIPLIPYGYN DVSKDSGPHH NDYEIEMMLK ELAANSDVTF
     L
//