ID   A0A158Q9Y3_ENTVE        Unreviewed;       481 AA.
AC   A0A158Q9Y3;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=COP9 signalosome complex subunit 3 {ECO:0000256|ARBA:ARBA00014878};
GN   ORFNames=EVEC_LOCUS3237 {ECO:0000313|EMBL:VDD88094.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000352901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000352901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD88094.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CSN3 family.
CC       {ECO:0000256|ARBA:ARBA00007084}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UXUI01007540; VDD88094.1; -; Genomic_DNA.
DR   STRING; 51028.A0A158Q9Y3; -.
DR   WBParaSite; EVEC_0000352901-mRNA-1; EVEC_0000352901-mRNA-1; EVEC_0000352901.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR10758:SF1; COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR   Pfam; PF01399; PCI; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Signalosome {ECO:0000256|ARBA:ARBA00022790};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        210..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          327..413
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|SMART:SM00088"
SQ   SEQUENCE   481 AA;  54248 MW;  50D706DCF770B869 CRC64;
     MSGGLDNYVK NVIAFTSAES YRELVELNRK ALTDVLEKSG VPLTQILEML NVEEHSLSFV
     TILLAKLNQA CSAANSEEIE ETLSQIEMFL PFFNRTQIIL APDICKVFSL FLSNHIKNVI
     LLLCFNLGIR FSDINFNEHI SRGILLLSGA INAIIGEPGE LTSLHSCLFC LCLKSKLFEP
     ALRFLETPVS RIMKETPGDK VDRGYMDSRF VLLYFYYGGL IYGALGRLDD SLLMMQNVLC
     IPALLTSAIM IEAYKKYLLM SLISHGKVKA LPGYRAMVVQ KLQRFCFEYQ FFENICTMDS
     SDKDLAQEIM NHLQAHHAVF FKDNNVGLIK RLARKMREAS IIKLSKTFLS VSLGDLARRC
     HLHDWGNAER YLMEMNAENK ICVTLDKEHG LVYFDEPKTV VDEETLNSVI KAGMNLTSLL
     KTYDTRLRTN YMYIARSTKV SALCAHDDEG FQQGTSGANV LPMMGIIPNA VVPSFELNMP
     S
//