ID A0A158QA76_ENTVE Unreviewed; 803 AA.
AC A0A158QA76;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=dynamin GTPase {ECO:0000256|ARBA:ARBA00011980};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
GN ORFNames=EVEC_LOCUS4028 {ECO:0000313|EMBL:VDD89277.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000432001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000432001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD89277.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR EMBL; UXUI01007743; VDD89277.1; -; Genomic_DNA.
DR STRING; 51028.A0A158QA76; -.
DR WBParaSite; EVEC_0000432001-mRNA-1; EVEC_0000432001-mRNA-1; EVEC_0000432001.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR CDD; cd01256; PH_dynamin; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF212; DYNAMIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT DOMAIN 30..296
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 511..616
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 644..736
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 618..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..772
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 803 AA; 90818 MW; B4B62DB26902F4C9 CRC64;
MAWANTGMQA LIPVVNRLQD AFAQLGTSLN FDLPQIAVVG GQSAGKSSVL ENFVGRDFLP
RGSGIVTRRP LILQLIQDRA EYAEFLHKKG QKFVDFDLVR KEIEDETDRL TGLNKGISPV
PINLRVFSPN VLNLTLIDLP GMTKVPVGDQ PPDIERQITD MILTYISRET CLILAVTPAN
SDLATSDALK LAREVDPQGL RTIGVITKLD LMDEGTDARD ILENRVFSLR RGYVGVVNRG
QKDIMGKKDI RAALDAERKF FISHPAYRHM ADRLGTPYLQ KTLNQQLTNH IKDTLPALRD
SLQKKLFALE KDVAEYKNFS PNDPSRKTKQ FTVDIERSIE GSSAKTVSTN ELSGGARINR
LFHERFPFEI VKMEIDEKEM RREIHIAIRN IRGIRVGLFT PDMAFEAIVK KQIERLKEPS
LKCVDLVVNE LANVVRQCTE CVARYPRLRD EIERIVTTNM REKEQIAKQQ ISMIVDYELA
YMNTNHEDFI GFSNAEAKAS SAQTKKNLGN QVIRKGWLSV HNISFVRGSK DCWFVLTSDN
LSWYKDDEEK EKKYMLPLDG IMLRDLEAGF MSRQHKFALF YPDGKNIYKD YKQLELSASN
LDEVDAWKAS FLRAGVYPEK EKPTEENGRT EEETSLDPQL ERQVETIRNL VDSYMRIVTK
TIRDLVPKAI MFLIVNKVSS FLRDGELLAS LYQIGDTESL MEESQLEAQK REEMLRMYHA
CKEALRIIGE VNMTTVATEA PPAVSTDWMR SNGPSPVPRP APQPPTGQRP APMPPRSANQ
SAPSFANRPL PTAPGLPAPL LPT
//
