ID   A0A158QB55_ENTVE        Unreviewed;       937 AA.
AC   A0A158QB55;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   28-JUN-2023, entry version 20.
DE   SubName: Full=BRCT domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000829501-mRNA-1};
GN   ORFNames=EVEC_LOCUS7779 {ECO:0000313|EMBL:VDD93028.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000829501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000829501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD93028.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; UXUI01009086; VDD93028.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158QB55; -.
DR   STRING; 51028.A0A158QB55; -.
DR   WBParaSite; EVEC_0000829501-mRNA-1; EVEC_0000829501-mRNA-1; EVEC_0000829501.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR   CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR   CDD; cd17724; BRCT_p53bp1_rpt2; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR   InterPro; IPR047250; BRCT_p53bp1-like_rpt2.
DR   InterPro; IPR047252; TP53BP1-like.
DR   PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR   PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF18428; BRCT_3; 1.
DR   SMART; SM00292; BRCT; 1.
DR   SUPFAM; SSF52113; BRCT domain; 2.
DR   PROSITE; PS50172; BRCT; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT   DOMAIN          710..812
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          1..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          652..695
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..126
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..237
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..287
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        300..315
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..410
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   937 AA;  103462 MW;  BA948810D00E652E CRC64;
     MSTSLEQPRE SNGADEKQEE LSEVGGQSAD AIVSDGNLKE SKKGLFGRSA EFLKSPEPNA
     MEVVEATERN GNVNEAVETS SPTNKSSGDS TEKEVDEKKL GSTLPADVVP ESDDRGNGKE
     SESEVPSKET VTVTVTVTEE VVEEVKADDV EMASDEKPTK EEEVAKEEEV EDREEAQGTE
     TKCTTEEGHA DGPPDTSIKG QAQEPGSETG TKRSRKSKQK TFKEEEPMNE RRRSLRTPKP
     TPVSIPPKSA TEKVTKKSAP KVEKAASETP VRGGGRKREE KAAETTPVKK SGSKPSSAKK
     SRSSESEKKP KAEQNSDAND PFNISNIDNH PVILSNIQIH AAQFGSLKFT KTSPGTSQYA
     LDQDFGNFRS RYEKTEQTAG ERRSNLTNMT PQSTPRKSLS ELSTSTSQRQ ESARKVKRGA
     SAKSVKESAR EENEPMDTSE PTTPKSAKRS RGAAKTPSTG KKSETSRKRT SSMNATPISA
     KQQKVEPEIP HLTPEEQFVV DHRENEHMPY KLGARVYALW NREYYSAVIT SDFDAAGRYG
     VTFVQDKLIR KLVVTGIIPL QALVGGIKVY ASDPEIPEKD SRLEEVEIIS SPSEKDHQKW
     AEGIFRVKIC ESGKTFDIAW DKLCFSAEEA KTLQTAKFNS VTDVIADNID SKEGRRTRAS
     RHSFAPEAAP SPSVSRPTPK RRANHADKPS EAPTTVEIGM TEKQVKQTKA AGDIFANISF
     VVTSAMRRMK EEEQGGFSKR EIRQMIEGCG GNVVEDFTKI PAGSKMFLIA DTHYRTHKYL
     SALARSVPCV SHRWIRECVE KGELLDYKPY MLQAGVSLLT NKLTPWHQSN NTLLSGKRIY
     IYTRNVIPDA SVPNFVQIWS PLVAEMGATV VSEIPKVSIY IFRSDGIDIL LTDATCTEDV
     IQQARKCDAL AIIEGSLPDP NAHERFRYDF VERPEGM
//