ID   A0A158QBV9_HYMDI        Unreviewed;      1300 AA.
AC   A0A158QBV9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=MIF4G domain-containing protein {ECO:0000313|WBParaSite:HDID_0000057101-mRNA-1};
GN   ORFNames=HDID_LOCUS572 {ECO:0000313|EMBL:VDL16745.1};
OS   Hymenolepis diminuta (Rat tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX   NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000057101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HDID_0000057101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL16745.1, ECO:0000313|Proteomes:UP000274504}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; UYSG01000076; VDL16745.1; -; Genomic_DNA.
DR   STRING; 6216.A0A158QBV9; -.
DR   WBParaSite; HDID_0000057101-mRNA-1; HDID_0000057101-mRNA-1; HDID_0000057101.
DR   Proteomes; UP000046397; Unplaced.
DR   Proteomes; UP000274504; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 3.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 3.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274504}.
FT   DOMAIN          38..242
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          470..659
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          674..907
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          358..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          865..893
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          947..1054
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1153..1172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1234..1300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          379..406
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        358..374
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        866..883
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        947..970
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        973..1028
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1240..1260
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1300 AA;  147750 MW;  453F6AE607770E30 CRC64;
     MKETSEKLIL KSDLLRENKV ARNNWPDESF FSLKDSTLKK NTAFVKKIRN FVESSKESLL
     KDFDGLNLSK YVAEVATAIT EPKLKLSDVQ FMLRLCSLMF RRYSEFESLL FEAWKKVFEK
     NKKVQNLSKL RVDMVLFADL IIVGVLPETE SLRMFSQLLA QVTIADKESF TNIGLITSFL
     RICGDDWAGL IPRKFKILAK ENGKTIQRSD FIPNERKVKY RGLFHEYYDA ALEHLMTMGR
     EARGVIVANR RAMFNKGEVH PDRQEKEQQL LTACRKFYES IALLADAVDK DSPTTVEEMT
     DCQDDEVDEL DKSFHSSSAF GDMTNCSVFE DDDARMFYES LSDLRSLVSS QIPFKDATIK
     PTLSSQQPKN DGDSSQDDAV NEEIEVEKIE NEIAAAAAEE DAIDENLVCP KTLENEERGE
     GENEQITASS DISNSCSTAS LTLLTAQPLD APLVLESAEE GAPSAKMLMD TFLNRLPNCI
     NRDLIDKAAC EFVTVLNKKG NRRRLLSVLA GVPRNRSDLL PFYARLVATL YPVAPDIGQD
     LVELLKQEFR WHLHKKDQMN IDSKLKTVRY IGELTKFRIF PGSEVLNCIF RLLSNFVHHQ
     IDMTCGLLDT CGRFLYRSPE THRRTKIYLD IINRKKLAMH MDQRYSQMIE DAIYTCDPPE
     RPCNFVGEDL TNMQRFVCSL LHGEMTRNNY KAITTALRKL DWKDVKLIEY MKRLFTQCWE
     VRYTSLEYLS SILSFLTEFQ PKFGIEVADN RNDPALHQRQ RSEARFLSGM YMYLIIDLPV
     LYGVLYDLIG YGVSFDYMRP SLIDPPTSVI RISMVLIIMD SCHAYFKKVT KSRRVKRFLA
     DFLHYYWWKR MHPIYLPLQL EQKTNGEKQV ENEPKEDEKS SESPSSNSEN SIDDPLLQVF
     NEFEGIPFPD AVEQQYEEGM RRLHLDPYAF YGLNTVEDFE RVIYEQCSQS PKSSTPEKLI
     DTTEPMETIS EENGSIVDEE DDIEEERETE EGDEEVYSDE DNDEDEDSAT LSGDESDSEE
     EDDGDEGTIN GDASFHTDLS DSDPLGSEEE EDEMVRLKLR PKHIKCPEDD EFVAELARLT
     SEALMPSTTG SPLGGVNPVA TGVPLNNPNA ASLPSLDSLG INVAAVKKTA SRSSTMNQTQ
     STTESIIAAL ESNGINENRE QSNSTKNSNS DQASSFMNFT LVVRRTENGG ASSRPCLVPI
     AVPQSVPFAS RLADLEAQEQ QEKARIKARV LEMHKAQKEA DATNNSNSET NLQLPSNVNR
     DRWVKYNHPK RAPDAEDVFG PSSVQMPPPP PSQSNRNSRR
//