ID A0A158QEH0_HYMDI Unreviewed; 275 AA.
AC A0A158QEH0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=IGFBP N-terminal domain-containing protein {ECO:0000313|WBParaSite:HDID_0000740401-mRNA-1};
GN ORFNames=HDID_LOCUS7402 {ECO:0000313|EMBL:VDL59720.1},
GN WMSIL1_LOCUS15031 {ECO:0000313|EMBL:VUZ57667.1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000740401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000740401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL59720.1, ECO:0000313|Proteomes:UP000274504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:VUZ57667.1, ECO:0000313|Proteomes:UP000321570}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMS-il1 {ECO:0000313|EMBL:VUZ57667.1,
RC ECO:0000313|Proteomes:UP000321570};
RA Jastrzebski P J., Paukszto L., Jastrzebski P J.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSG01010932; VDL59720.1; -; Genomic_DNA.
DR EMBL; CABIJS010000719; VUZ57667.1; -; Genomic_DNA.
DR STRING; 6216.A0A158QEH0; -.
DR WBParaSite; HDID_0000740401-mRNA-1; HDID_0000740401-mRNA-1; HDID_0000740401.
DR Proteomes; UP000046397; Unplaced.
DR Proteomes; UP000274504; Unassembled WGS sequence.
DR Proteomes; UP000321570; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.
DR GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR011390; IGFBP_rP_mac25.
DR PANTHER; PTHR14186; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14186:SF19; ZGC:85888; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00219; IGFBP; 1.
DR SMART; SM00121; IB; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..275
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040669615"
FT DOMAIN 33..121
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
FT DOMAIN 162..262
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 275 AA; 30668 MW; 62F44A8F52F31F3F CRC64;
MTFSRLEVIL SIIFGLLILS STVFSKYDST ETPLDACAPC DESKCPPVTM CPVGEVKDYC
GCCSVCGLEQ GHRCNTRQEL QDMFSGKRRH GYYGACGRHL ECQPRTDIDE KSEVENVCVC
VKPGRFCASN GETYSACELE AIQAKSFGEI FLISYDDCKS EPKIVAASES QRVPGGNKTT
FWCEIKGYPL PTVTWYYFAP GGSYEAILLP GDSDEMSVSL RGAPPGRRII SHLQIRRFDI
KYEGIYQCYV ENDLGSDRRN ITAIYTPPES NPREL
//
