ID A0A158QF37_HYMDI Unreviewed; 775 AA.
AC A0A158QF37;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Axis inhibition protein {ECO:0000313|WBParaSite:HDID_0000828901-mRNA-1};
GN ORFNames=HDID_LOCUS8287 {ECO:0000313|EMBL:VDL60605.1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000828901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000828901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL60605.1, ECO:0000313|Proteomes:UP000274504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSG01011057; VDL60605.1; -; Genomic_DNA.
DR STRING; 6216.A0A158QF37; -.
DR WBParaSite; HDID_0000828901-mRNA-1; HDID_0000828901-mRNA-1; HDID_0000828901.
DR Proteomes; UP000046397; Unplaced.
DR Proteomes; UP000274504; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR043581; Axin-like.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46102; AXIN; 1.
DR PANTHER; PTHR46102:SF2; AXIN; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 10..143
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 685..775
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT REGION 161..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 775 AA; 84204 MW; 9F79F0F46D39640D CRC64;
MDAHHPLSHQ LDTLLNDSEG VQQFHKFLSS TFSSGHLLDF WFACKGFRSI VDGDDQLKLL
QVAKAIYRTY IKTDAALSVP VNDSTKREIR STLTAFSQSY HNSINGEKRF PVLRSLFDAA
QADIQNLLAR SYFLEFLQSD SYRMIHQSLS ALECNSSLPG KSHHGFTDQS DNSKRGNYSS
SNPQKCRNQS GSGECVSQPT MDPTDQNTST CIMDQCDMSG LPSTAHAAKA STCGTISSDK
SRRTTAETGI PGPRELVTAS ELITYINPSD RAVAAPNNNP NTTSTTTNPE NDHPTSSKPP
PLMGSNAVPT NDATTTTTTT TRKPGTNLAE IDPSAFAQTL SHRLEKVKES RGKMERLLSR
MQPIDPEETG GEDAELASIH AEVVKPPTPP LPIRSTRLSS SSRRATSAAS GDLLRKKLSA
LLPPSAVSGV PVPAVPDDAQ VILEDHCSRI WTDERRGQPL NVCRKGGSGR RSDVYSISSF
DSGVGTCGAG GLNSSDSESC VSRAAAFHHH HHHHQSYQRW NYAPPSQQPA CSFCRRTPSM
SSTPATHRKE VITSGGSSGS GNYRWGVQYT RMQQQYHHSS SHHYNLEESG RAMRSRSLTS
DSPSVFDSGL SSTYDHLPPP RRSRHDETHK IVPERQKFAA AAAGSGTIAS AVTTRCTESA
LLKTAPGGNG IYPPSSLLSP PTGPTFSLVV GYYLCDDPVP YRTVWTGPFV SPDSPPSITL
GQFKQLVAKK GVYRYFFKTA SDDFGTGCVH EEIGDDNAVL PLWEGKVIAR VERAD
//
