ID   A0A158QK83_HAEPC        Unreviewed;       571 AA.
AC   A0A158QK83;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=IRG-type G domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000412901-mRNA-1};
GN   ORFNames=HPLM_LOCUS4121 {ECO:0000313|EMBL:VDO22464.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000412901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000412901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO22464.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO22464.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   EMBL; UZAF01016176; VDO22464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158QK83; -.
DR   STRING; 6290.A0A158QK83; -.
DR   WBParaSite; HPLM_0000412901-mRNA-1; HPLM_0000412901-mRNA-1; HPLM_0000412901.
DR   OMA; VLWEIPY; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR14143; INTERFERON-INDUCIBLE GTPASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR14143:SF1; IRG-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..571
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033250413"
FT   DOMAIN          62..270
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   571 AA;  64618 MW;  2B2316DA796EF5A6 CRC64;
     LSGIVYSIHH VLVVIDIVLL YSSNPLTFQS NYDEYPIYNP VTDYTFKSGM TFQQGAYPID
     TTRINIGFVG RQGAGKSTLI NAIRGLTMSD PQAAGRHPCN HMEPFRFMEE EFQNMILWEI
     PYPRAFVSVS DIYDRNMGFE RFYESHKLNL FRRIFLLIAD GAPHDDDISF ARIVHSRRTP
     LTMLSTKSDD DLDAEAREFG RSIDSSLKRE YDARARSVFT KSLMMKAQIL TSVELLLISS
     PVVKNLLSGT IGYLHYKLDE DKLLELLELG PGCHYTLENK LRKTVRNTSS TFPPRHIQKS
     TVLADAGFEI MFGTDDRVFG NLEPKSTVRR AGRTTFNYGF IGGNGVGKSS MINAMRGMSS
     KHPLAAGKTR IKRGACERFE FDDDLLKYSV TLWELHYPKK ISAYFEFIDR HNIASFTAIF
     VLIDETPTDE DLSFSKIAHR RNASVVFLSS KSDRKLAARS RSDEIPVCDL LKQRFVDKGL
     ARFDRTLSTS APELCGRVHV FFVSAPVFRA LRIGDALGMQ FILHERAVFD FLKQKRIVAD
     LLDSPSPDEF KDTVHTNPNL DTAGVAIIES S
//