ID   A0A158QLA9_HAEPC        Unreviewed;       855 AA.
AC   A0A158QLA9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=G-patch domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000612101-mRNA-1};
GN   ORFNames=HPLM_LOCUS6113 {ECO:0000313|EMBL:VDO28032.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000612101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000612101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO28032.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO28032.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR017706}.
CC   -!- SIMILARITY: Belongs to the TFP11/STIP family.
CC       {ECO:0000256|ARBA:ARBA00010900, ECO:0000256|PIRNR:PIRNR017706}.
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DR   EMBL; UZAF01016442; VDO28032.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158QLA9; -.
DR   STRING; 6290.A0A158QLA9; -.
DR   WBParaSite; HPLM_0000612101-mRNA-1; HPLM_0000612101-mRNA-1; HPLM_0000612101.
DR   OMA; QNEFNPH; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000390; P:spliceosomal complex disassembly; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR022783; GCFC_dom.
DR   InterPro; IPR022159; STIP/TFIP11_N.
DR   InterPro; IPR024933; TFP11.
DR   InterPro; IPR045211; TFP11/STIP/Ntr1.
DR   PANTHER; PTHR23329:SF1; TUFTELIN-INTERACTING PROTEIN 11; 1.
DR   PANTHER; PTHR23329; TUFTELIN-INTERACTING PROTEIN 11-RELATED; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   Pfam; PF07842; GCFC; 1.
DR   Pfam; PF12457; TIP_N; 1.
DR   PIRSF; PIRSF017706; TFIP11; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW   ECO:0000256|PIRNR:PIRNR017706};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW   ECO:0000256|PIRNR:PIRNR017706};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017706};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728, ECO:0000256|PIRNR:PIRNR017706}.
FT   DOMAIN          175..221
FT                   /note="G-patch"
FT                   /evidence="ECO:0000259|PROSITE:PS50174"
FT   REGION          230..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   855 AA;  97920 MW;  730A79E20D62713E CRC64;
     MAEEDEGMEA FDFDERDLEF ALNPGRRHYQ TKNQATYGIW ADRESDEEEA YGRPSFGMSY
     VIIFRKKARK DYSAPINFIS GGIKQGSSLD PSDKVEPFAF VSPHLLFRKR NSSKMGFQLK
     ENVRNADDAP IEIISRKERR KQKSVGANVF AGIRTSAVTG AVDPNAPSDW TKFGKGEVIK
     NMMKSMGYKE GEGLGAARQG IVEPVQATVR KGRGAIGAYG KEAVGPKFGE SAADAQRRIS
     DQKQESNVEE LSTPQLKNAW KKAAKVKTRY KTIDEVIEEG GSIGFRSSVK TGVKVIDMTG
     PEQRVYSGYD SFSMKSRAAF NDISDRDVFD VPELMHNLNL LVDLTEENIR RNDSQLKSIK
     DRTTALEYDL EQAKLLHETE AKEYERIKEV FELIENFSKR KGDDLPSMNE CQQLFVKLRS
     EYKEEYQLFD IETLAIQLVL PQIVDHFSKW KPLDPEHLIY GVDLMKEWRD ILVDKESVSI
     FSGSILHYFL LCRFNAETHG YSALRSDRLT AYDRLLWEGW LPSLRRASLT WDPRDHMEPM
     LRVIEMWLPV LPGWMKENIL EQVIIPRIED RVSSWDPLTD SIPIHSWLVP WLAVLGDRLQ
     PVLAPIRQKL AKALRAMAIL KPWCGVWTPA TMSAFLAQNV VPKLEKCLDT MNLNPRENKK
     YEEWYSCMSW IGMISADTMA SIVTKYFFPR WYSALCQWLD SPRAILDEVK MWYREWDGRI
     PPQIRDFPTI KENLRRGMVA VMESSQGLRV YNGPPPPPIA QAAPPPPPPS ALRPNMGMPI
     SSAHMSLKEM LERIAAQHDL THIPQRDRLK EGRQVYWFGT QSIYLDRNIV YVLDTHSFSW
     RPVGMEELLK LAGVG
//