ID   A0A158QMG1_HAEPC        Unreviewed;       479 AA.
AC   A0A158QMG1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Aldehyde dehydrogenase, mitochondrial {ECO:0000313|WBParaSite:HPLM_0000835401-mRNA-1};
GN   ORFNames=HPLM_LOCUS8346 {ECO:0000313|EMBL:VDO34585.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000835401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000835401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO34585.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO34585.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; UZAF01016840; VDO34585.1; -; Genomic_DNA.
DR   STRING; 6290.A0A158QMG1; -.
DR   WBParaSite; HPLM_0000835401-mRNA-1; HPLM_0000835401-mRNA-1; HPLM_0000835401.
DR   OMA; ENCSATS; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF302; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 2.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          39..142
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   DOMAIN          147..470
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        247
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   479 AA;  52376 MW;  59F4DB337694E2AE CRC64;
     MLRTLLSRVS PQLRRASSAP PAISNVEPKF TKLFINNEWV DAASGKTFKT FHPATNKLIT
     DVAEADKADV DKAVKAASDA FRLGSPWRRM DASQRGVLMN KLADLMERDK VYLASLETLD
     NGKPYAESFF ADVTLAINCI RTSYLQWNFP ILMQAWKLGP ALAMGNVVVM KPAEQTPLTA
     LHVASLIKEA GFPPGVVNLL PGYGPTAGHA ISSHQEVDKV AFTGSTEIGR IVMRAAAESN
     VKKVTLELGG KSPNIIFSDA DLDSAIHLAH LGIFFNQGQV CCAGSRVFVE GKIYDDFIAR
     SKELAEKRKL GNPFDLQTEQ GPQIDEEQLK TIQRYVESGK KQGAQLVTGG KKWGDKGFFF
     EPTIFANVKD EMVIAQEEIF GPVMSVIRFD SMDHLVEIAN NTIYGLAAGV VTKDLDKALY
     VANNIRAGSV WVNCYHAFDA AAPFGGYKQS GIGRELGEYG LEAYTEVKTV TIKVSQKNS
//