ID A0A158QMX3_HAEPC Unreviewed; 1257 AA.
AC A0A158QMX3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=MIF4G domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000940301-mRNA-1};
GN ORFNames=HPLM_LOCUS9395 {ECO:0000313|EMBL:VDO37371.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000940301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0000940301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO37371.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO37371.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR EMBL; UZAF01017053; VDO37371.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A158QMX3; -.
DR STRING; 6290.A0A158QMX3; -.
DR WBParaSite; HPLM_0000940301-mRNA-1; HPLM_0000940301-mRNA-1; HPLM_0000940301.
DR OMA; EMELWED; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT DOMAIN 608..849
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..970
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1257 AA; 141032 MW; 64A7B56670ADF190 CRC64;
MSSAISRERG KGKPYSQDAL NVGASHHAGG TSLPMGAPQP SFATPTIPNL PTPQQEYDMT
SPTMCLPVGT TIHPMGYGMS FLQHGGHYVA RPGNAPPTHM RAQPPQQYYP PQQMFVQQQQ
FYPGPQYSRQ PGMDYDPHAA TMSTMYMGQQ ITHPTPMTMQ PPPQQVQQQR NKNILTIQDP
NTLEEVDLGA RSDSATETKK DEPKGRKDVD ETEQKKSEVM RQFTRQLQER NEMDQAESSG
AGSLPSKPNT SREHTPVSTL NPEEQKAMSG EGVATTVETP PATEPILKDK TNETEPLTKD
ASQAESKPEP AVVIEEPHKI DEASIPAPST PAQTTTSVSA PPLDPDPVKE EHEAHEERKT
LPEIRTDSEA PNSTTPGGSA VVDDQEESLK SDIATAETVT ESTVDHGSVA DVEAEDSTTE
VVDTPDAPTP DTEEEERRKA EEEEERKRQR LAELDTLLHS LLENPAEVDS DNLIYGRAFL
YCVRDIEKEF KRCPCPLSHD KIVKLGIDLN SMPKGNDNKK QHSFIPPWMN QSRQSNKPSN
RPYGGRFSHN DHRGGKGGNK KFPPSARPSI ERNIERGVPL HKAENAWKPE KIRPEDLEKE
EARIKLLLKN VRSLMNKITP TTKDDLIKEF LGYDVSSSPE QLASVINIIF DKAVEEPKFC
PIYAEVCKQQ VDKELKENSK LSLCRNALLN RAQETFVNKT WEEERNVKVK AIEEEEDPKK
KLQMQLDLQE ADNKFRRRKF GNITFIGQLY RQSLLSTKIV QWCLFDLIKH THRNPETGKL
PEPPFDEESL QCAIQLIESL GKQLDVSSPD FNGKEYLDQT LHHLECISSM TSNKIRFMIM
NVVELRQSRW IPRKGADQGP KKLAEIHNEI KREQMENQLQ RDQYDRKLRT GGSTSQHGRN
PPPPRNSLDN RFGPKGGDRR SIAASKAKQT PSSVQPKSVS LLLKGDNSLG GSNRKTWHQG
SGGGGNNSTV EAAKVGWQKP GRDEIPRKNS SVDERATTLA TTKSGSVGKP DTTPVIACLL
VTEPDSEELK AMREDLYKKI GKEVAAILET YDEGDMKLEE CVNDIFKMVD AEQYGRPSVN
EVFSRFTEYA VEKVRKPLLP KLGHMLCLAL QNSEHRSEAL AGMAKYCSLA VECEMWMDIP
DIWSKLAELL VNAVYCDPNV ITGVRPSFKD FTNVFIEASK DERKDKPYEL LVVSLKRMAE
MNAKVDSQDH ATMSSFVYSE ELPFLQEIDK ERLENALRAC RPDVPGFDDL YAVLHHH
//
