ID   A0A158QP10_HAEPC        Unreviewed;       278 AA.
AC   A0A158QP10;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=PPM-type phosphatase domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001166901-mRNA-1};
GN   ORFNames=HPLM_LOCUS11661 {ECO:0000313|EMBL:VDO43463.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001166901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001166901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO43463.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO43463.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SIMILARITY: Belongs to the PP2C family.
CC       {ECO:0000256|RuleBase:RU003465}.
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DR   EMBL; UZAF01017627; VDO43463.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158QP10; -.
DR   STRING; 6290.A0A158QP10; -.
DR   WBParaSite; HPLM_0001166901-mRNA-1; HPLM_0001166901-mRNA-1; HPLM_0001166901.
DR   OMA; RASEHCQ; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR000222; PP2C_BS.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR   PANTHER; PTHR47992:SF105; PROTEIN PHOSPHATASE 1B; 1.
DR   Pfam; PF00481; PP2C; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS01032; PPM_1; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW   ECO:0000256|RuleBase:RU003465};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          9..276
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   278 AA;  31171 MW;  1B638DD67AA87BA8 CRC64;
     MTLSEPLQLI SVLGCRRGQR EDMQDAHLLI EDLSLNLTFV SRCALYAIFD GHAGTRAAKY
     CEDKVPDVLK KKLSSYSDLS TLEKQLKRVF TETFKSIDEG FLAEARKTKP VWKDGTTVTC
     VLLLNDSLYV ANLGDSKAIV CRSKDCGFSP IELTVNHNPT MYEERVRIQK AGGTVKWDGR
     VNGIIEVSRS IGDGQFKTYG VTCIPDMKKL TITERDRFLI LACDGLWKSF GNEEAITYVN
     ELLEKSCKVS SEGLRVKMLT WRRSAKKNIA NILICLGP
//