ID   A0A158R2E7_NIPBR        Unreviewed;       853 AA.
AC   A0A158R2E7;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial {ECO:0000256|ARBA:ARBA00020084};
GN   ORFNames=NBR_LOCUS15710 {ECO:0000313|EMBL:VDL79304.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001570901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:NBR_0001570901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL79304.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00007569, ECO:0000256|RuleBase:RU003456}.
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DR   EMBL; UYSL01021851; VDL79304.1; -; Genomic_DNA.
DR   STRING; 27835.A0A158R2E7; -.
DR   WBParaSite; NBR_0001570901-mRNA-1; NBR_0001570901-mRNA-1; NBR_0001570901.
DR   Proteomes; UP000038043; Unplaced.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00105; KH-I; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR   Gene3D; 3.30.460.80; NADH:ubiquinone oxidoreductase, 30kDa subunit; 1.
DR   HAMAP; MF_01357; NDH1_NuoC; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   InterPro; IPR008962; PapD-like_sf.
DR   NCBIfam; TIGR01961; NuoC_fam; 1.
DR   PANTHER; PTHR10884:SF14; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR10884; NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3; 1.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR   SUPFAM; SSF143243; Nqo5-like; 1.
DR   SUPFAM; SSF49354; PapD-like; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|RuleBase:RU003456};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW   Translocase {ECO:0000256|RuleBase:RU003456};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003456}.
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        75..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          321..441
FT                   /note="MSP"
FT                   /evidence="ECO:0000259|PROSITE:PS50202"
SQ   SEQUENCE   853 AA;  94336 MW;  0D19897681527942 CRC64;
     MQRSFLSPPT TPNARQSRTN VELSAREAAI LAAMCGFAAF NLNSTDAKTM LHVFTLVPGI
     VFTFRIIAIN NDSSTLSVST MAVFWMYYGM GLICEVLLGY DESHAVVQLA LVGALGVAAY
     RGIPSAEQSS SDFRTILSGS YSLIQQRTQK SPTQVRQARK RSLQSLSVET AVNIGTRTRT
     MSTQSCSDLT SLTAREITDD LKTLMTAIVS DTDTALEMFP SPASLTIASS QKTTSKNKAA
     SPLSLMTARL TDPDTAIEMF PTPVPSQKSA KGLVTAVQSD TRTAVPIRSP ATSATAAGSQ
     VGPSKLLDEM TESPVLIDHS GLIAEPLKTL RFKLPSDEQT ITLKNVSNQQ FRWTVKTNAI
     YEIQAFPAHG VIHRGEEIQI KVVLNAENIA VPGANCDDDK AILQLETDAD RCIRVRITGV
     PLAVAAAKIE IHELVLAIIR ESFRHTVIVP SRFVGLIIGR NGKKIENVKL TTGANIKIGR
     NENGFTKVSI VGNYRRIVAA VTMIKDRLDS AGTATSVYDR PDRQEFHELL NEAMGDSSII
     HHYNTYLKNA LQVAYSSLSY EKFIAAPVYA TQPFAWTAPT PPILMELGML PILARPLSRG
     LQRSVAAASL STTSVAKQTE QKQEKKKGPT ILKLDEEKKK KLANFGRYVA ECLPKFIQQV
     QFAGGDELEF LIHPSGVIPV LSFLKGNHSA QFTNLTFICG VDVPTRQNRF EVVYSLFSVR
     FMARCRIRTY TDEVAPLESA TSVFRGANWY EREVYDMFGV WFNNHPDLRR ILTDYGFEGH
     PFRKDFPLSG YNEVRFDPEL KRIVYEPTEL AQEFRKFDLE TPWETFPAFR ETSITSGYEQ
     IHVGDKPAAP KAK
//