ID   A0A158R445_9BILA        Unreviewed;       353 AA.
AC   A0A158R445;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=TGF_BETA_2 domain-containing protein {ECO:0000313|WBParaSite:SMUV_0000236701-mRNA-1};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000236701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000236701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TGF-beta family.
CC       {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR   AlphaFoldDB; A0A158R445; -.
DR   STRING; 451379.A0A158R445; -.
DR   WBParaSite; SMUV_0000236701-mRNA-1; SMUV_0000236701-mRNA-1; SMUV_0000236701.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   CDD; cd13761; TGF_beta_BMP5_like; 1.
DR   Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR001839; TGF-b_C.
DR   InterPro; IPR015615; TGF-beta-rel.
DR   InterPro; IPR017948; TGFb_CS.
DR   PANTHER; PTHR11848:SF298; PROTEIN 60A-RELATED; 1.
DR   PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR   Pfam; PF00019; TGF_beta; 1.
DR   SMART; SM00204; TGFB; 1.
DR   SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR   PROSITE; PS00250; TGF_BETA_1; 1.
DR   PROSITE; PS51362; TGF_BETA_2; 1.
PE   3: Inferred from homology;
KW   Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW   ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..353
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007631485"
FT   DOMAIN          215..353
FT                   /note="TGF-beta family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS51362"
SQ   SEQUENCE   353 AA;  40828 MW;  81C914768A8692DA CRC64;
     MRCWWQTAFT VLTILCEKGV FTHFSTAFYV DNDQLQSVPL HVTKKVGAYL ESNIVELLGI
     KRHGYGVKDE LATRFMTQLY KSRFYDFDRC CYFTICFLLR YLENGTDMYG AGEKAIALGE
     ADTIVSFRPH AVNDRYLNNS TRLTFKCPEL FSEGRLLYSE LRISLENASK PLYLAVEFDD
     HRIFSGDKRS LSDFGKWYGF GIASFSDSRQ RVHLRTKRNI PIGQENFEDP STLFTSKPKS
     LFTWKSGYGN ECSVKSLYVD FKYLNWQEWV IAPDGFHAHY CDGSCSFPLT SRMNATNHAI
     VQTLVYLIDP KKTTEPKCAP TLLKPMKILF VDYNRNVILK RYRDMVVEDC GCQ
//