ID A0A158R9F5_TAEAS Unreviewed; 1287 AA.
AC A0A158R9F5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=FERM domain-containing protein {ECO:0000313|WBParaSite:TASK_0000717001-mRNA-1};
GN ORFNames=TASK_LOCUS7171 {ECO:0000313|EMBL:VDK37970.1};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000717001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000717001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK37970.1, ECO:0000313|Proteomes:UP000282613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRS01018582; VDK37970.1; -; Genomic_DNA.
DR STRING; 60517.A0A158R9F5; -.
DR WBParaSite; TASK_0000717001-mRNA-1; TASK_0000717001-mRNA-1; TASK_0000717001.
DR Proteomes; UP000046400; Unplaced.
DR Proteomes; UP000282613; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45858:SF5; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000282613}.
FT DOMAIN 19..362
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 945..1175
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1224..1287
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 381..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..791
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1287 AA; 140976 MW; 4F3BEC683A862AFD CRC64;
MPNATNSSSV NLKTASKSLQ IQVELLDSTR QHFQMSPRSS GQDLYTALMD RLGVLEADFF
DLEYVNRDGN TCWLDHLKPL CKQHNAEKEF VFTFCVKFYA PHPNLLEDEF TRYLFALQIK
RDLYRGQIQC SENTAALLAA FIVQAEIGDY LEDTFLDRSY LAGLRLVPSA TPEFLDKVME
CHRSLIGQTP TEADSSLLDT ARKVEMYGIR LKPVKELIKN LSPTHLMGLE KEQVNGIRSS
KQSNVTEYAQ IRDLVMGPLG VSENSPEFSQ IGGNGQDWKG SDGMPLNLAV SHAGLFVFQG
VSKVNTFSWA RIRKLSFKRK KFLIKLHPEG YDAVEFFFES RNECKGFWKQ CIEHHAFFRC
QSVKAVGKSA KVSKNATQVA SASSTGRVHR SPGRGCSGAS NPSQPILTSA LSISCDANHF
HHHHHIIQQQ QQQTTSTAQQ PSQVTARSLP LTGTVDDAAV PSFVQLPTGG SLRYPQRVML
VVPRRADGTI GRTTATTTQA VAATGGGGFL VMLPTTSADQ QQQNAWLSAI QQQQQQQRAF
SPVNGKEPTY STLQTSLVMT TQAPRNGNLQ DGGNVCSQTL GHLPTARVLS PNFLTTSQSG
LSTACTVIPS AHRPASGRVV YVDSATGRLI SDSQLVAVSR PLNMMGSGFS SAPASQAPTV
ATSPIGGPYG SSTAAAAAVI GGPIGIVPQD IVNTAPIPGG SNTTSSLPQL LRSRPHGPPP
PAPERRDSVQ PRDRQLSSST LDSGITSKSA SLSRPSFDAS AAGLEEDEEL PPPPPPPPME
MEDPDPAHPF PFNVIPVEGD FATRRPMQAS CLSLAARSVR SSCQSLLPTD EDLDEDGEEL
ESRSLSHRQF ASRSASLHRP LVKRDRCAEV STITQDDMAT ALAANRSSTN SSATGSVAAA
TSSASSRSLV SLSSKSRRDD RSLRSSRRGS MSGSSRNLPR APASVAYHLL RELTMTERTY
KKDLDVVCEG FREAFTEESK DCVAVESVFS KLFTLLDPLR AQAIDFLNEL ESRFAAWSTR
LESTSRSSHR LSSAASAVTS ASGSASSASA SATSANVDAD SPTTPVRIGD LFVTNLKMLQ
LYRSYLRETE CLIIDLERLV RSRASFQSKM QAYEAQKSCY LPFYAFLLKP MHRLLQYRSV
LERLMRHYNE SNPDMQDCRV AHARLLDTIQ SQWDSYKRCE NLYKSLEVER DLVGVQTTSE
TTTVTSSGSG REKPTGWLAS RSRQFIREGL LQKLSKKGYQ QRMFFLFSDQ LIYASRTNAP
FLQFKVSLIR DTPTLLTVCD LTCASRP
//
