ID   A0A158R9Y1_TAEAS        Unreviewed;       362 AA.
AC   A0A158R9Y1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=S5A_REDUCTASE domain-containing protein {ECO:0000313|WBParaSite:TASK_0000800201-mRNA-1};
OS   Taenia asiatica (Asian tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX   NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000800201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TASK_0000800201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC       {ECO:0000256|ARBA:ARBA00007742}.
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DR   AlphaFoldDB; A0A158R9Y1; -.
DR   STRING; 60517.A0A158R9Y1; -.
DR   WBParaSite; TASK_0000800201-mRNA-1; TASK_0000800201-mRNA-1; TASK_0000800201.
DR   Proteomes; UP000046400; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR   InterPro; IPR039357; SRD5A/TECR.
DR   PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR10556:SF28; VERY-LONG-CHAIN ENOYL-COA REDUCTASE; 1.
DR   Pfam; PF02544; Steroid_dh; 1.
DR   PROSITE; PS50244; S5A_REDUCTASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          250..337
FT                   /note="Steroid 5-alpha reductase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50244"
SQ   SEQUENCE   362 AA;  40953 MW;  1C3125308A3642A0 CRC64;
     LSSPLIANES TGYYDYGKEF CVNKTCPQVT IIHFASEKVL LTLNDVSPST SIRVLKEKLA
     SRGNLVLLSP LNINRQKIQV KSHFASLGTS RHFFHVSNFY TFVGGKILAN SFRLNEIEGA
     GKTSEVRLFY KDLGPQVGWS TVFYLEYAGP LVIYLVVWAM RQPRCLLNVL SPMQTDVGLR
     CLAGLCYVGH FVKRLLETRF VHRFSHATMP LASLFRNCLY YWLFALSIAY FTTHPLYTPP
     SFGWPQVYAG LGLFLLGELG NFCCHIALRN LRPAGSTLRQ MPHPVPNSPL TFLFKYVACP
     NYTYETLSWI GFTVMTQTLP AAAFTMLGFW TMAQWARNKL RAYRSEFASC PKGLKAIVPL
     IY
//