ID   A0A158RDU6_HYDTA        Unreviewed;       733 AA.
AC   A0A158RDU6;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Amiloride sensitive cation channel {ECO:0000313|WBParaSite:TTAC_0000610001-mRNA-1};
GN   ORFNames=TTAC_LOCUS6085 {ECO:0000313|EMBL:VDM30232.1};
OS   Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX   NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000610001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TTAC_0000610001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM30232.1, ECO:0000313|Proteomes:UP000274429}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UYWX01020293; VDM30232.1; -; Genomic_DNA.
DR   WBParaSite; TTAC_0000610001-mRNA-1; TTAC_0000610001-mRNA-1; TTAC_0000610001.
DR   Proteomes; UP000046396; Unplaced.
DR   Proteomes; UP000274429; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   InterPro; IPR001873; ENaC.
DR   Pfam; PF00858; ASC; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274429};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        136..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   733 AA;  81910 MW;  62684A7E41B8D7AF CRC64;
     MKTSVEFGIL RHDAPPIPPS RSSKVPRELL LNNQECIPAG SGFQGHYHFA EVAKDVSRHP
     LSTIAAVTTL ELREAATAAP PPMTNTSSDL LAATKSPLPP HMIALTPQTA PFTVDANPPA
     PEMLQQHKQE ACQRKWLIRV GVLLAVALVL ICVVYQICAW TSRWQKRRAF LLVQRTFASS
     VNNERRNGEM EFVMSGVNIT ICNANPFRGS AIFDLPSGSY LYDMLTGIHS GAVRIPDFAK
     ELSKQSLSTL IAISHHLPDM LKSCTINGLS CGTEEFESVI NFNRLCFRLA LNSSARDVRL
     ILDPQEHEYL LPNDAIVGFY LSVDNSRDQI LSSRMGLKQY ERSIDILQPP SESDELFVGS
     QFQTFIQVGF SDTPIPPLNS LSSISKAQIF RSTIRSVVQV AKPVFSSRFL QLREPITLRG
     TSRMAKARLV QQWAYLRHEN TSAVVVIENL ALRLGNLKKD FDGMLQSLAE LRAAQHMTSA
     FEPSKWDFVE TCISPTGTAL NTIVNFTDGF YDHLCRLLDS RDQDSYLIRN IHCDVDQPQL
     RPPPSTSETG STLQLFVVQM LFSRSHTTNQ RIIQLLRRQV SLLSIVNQEL QQHYTAGNMD
     GVELLECTRC ERLGGGGSDV RTSMSCRRMD RKPKVNMTQH WELFKKFNQA IAACTQRLDA
     LNKDLEATTM ANLKHIQAFL RGVGSDAAEV GSATHGPPGK PVSDEVRSLE EEARDVAFAF
     TWKMWFQVYT DGQ
//