ID A0A160F2U3_9BACI Unreviewed; 810 AA.
AC A0A160F2U3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Negative regulator of genetic competence ClpC/MecB {ECO:0000313|EMBL:ANB60566.1};
GN Name=clpC {ECO:0000313|EMBL:ANB60566.1};
GN ORFNames=GFC30_103 {ECO:0000313|EMBL:ANB60566.1};
OS Anoxybacillus amylolyticus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX NCBI_TaxID=294699 {ECO:0000313|EMBL:ANB60566.1, ECO:0000313|Proteomes:UP000076865};
RN [1] {ECO:0000313|EMBL:ANB60566.1, ECO:0000313|Proteomes:UP000076865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15939 {ECO:0000313|EMBL:ANB60566.1,
RC ECO:0000313|Proteomes:UP000076865};
RX PubMed=16682297; DOI=10.1016/j.syapm.2005.10.003;
RA Poli A., Esposito E., Lama L., Orlando P., Nicolaus G., de Appolonia F.,
RA Gambacorta A., Nicolaus B.;
RT "Anoxybacillus amylolyticus sp. nov., a thermophilic amylase producing
RT bacterium isolated from Mount Rittmann (Antarctica).";
RL Syst. Appl. Microbiol. 29:300-307(2006).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP015438; ANB60566.1; -; Genomic_DNA.
DR RefSeq; WP_066322120.1; NZ_CP015438.1.
DR AlphaFoldDB; A0A160F2U3; -.
DR KEGG; aamy:GFC30_103; -.
DR PATRIC; fig|294699.3.peg.95; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000076865; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000076865};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 3..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 417..452
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 413..463
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 810 AA; 90345 MW; 9727CBD87242A7B7 CRC64;
MMFGRFTERA QKVLALAQEE AVRLGHNNIG TEHILLGLIR EGEGIAAKAL IALGLGPDKI
QKEVEALIGR GHESSQTIHY TPRAKKVIEL SMDEARKLGH SYVGTEHILL GLIREGEGVA
ARVLNNLGVS LNKARQQVLQ LLGSNESISG HQGSASHVST PTLDSLARDL TAIAREGSLD
PVIGRSKEIQ RVIEVLSRRT KNNPVLIGEP GVGKTAIAEG LAQQIVNNEV PETLRDKRVM
TLDMGTVVAG TKYRGEFEDR LKKVMDEIRQ AGNIILFIDE LHTLIGAGGA EGAIDASNIL
KPSLARGELQ CIGATTLDEY RKYIEKDAAL ERRFQPIYVD EPTVEESIQI LKGLRDRYEA
HHRVSISDEA IVQAVKLSDR YITDRFLPDK AIDLIDEACS KVRLRSFTTP PNLKELEQKL
EEVRKEKDAA VQSQEFEKAA SLRDTEQRLR EQLEETKRAW KEKQGKENSE VTVEDIAMVV
SSWTGIPVSK LAQTETERLL KLEEILHSRV IGQEEAVKAV AKAVRRARAG LKDPKRPIGS
FIFLGPTGVG KTELARALAE AMFGDEDALI RIDMSEYMEK HSTSRLVGSP PGYVGYEEGG
QLTEKVRRKP YSVVLLDEME KAHPDVFNIL LQVLEDGRLT DSKGRTVDFR NTIVIMTSNV
GADALKRHKY VGFNVQDESE KYKDMKGKVM EELKKAFRPE FLNRIDEIIV FHALEKPHLA
QIVNLMAEQL VKRLKEQDID LELTQAAIEK IAAEGYDPEY GARPLRRALQ KHIEDRLSEE
LLKGTIAKGQ KVVVDVKDGE FVVLSEQTVQ
//
