ID A0A160FJD5_9BURK Unreviewed; 347 AA.
AC A0A160FJD5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:ANB72450.1};
GN ORFNames=AYM40_08815 {ECO:0000313|EMBL:ANB72450.1};
OS Paraburkholderia phytofirmans OLGA172.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1417228 {ECO:0000313|EMBL:ANB72450.1, ECO:0000313|Proteomes:UP000076852};
RN [1] {ECO:0000313|EMBL:ANB72450.1, ECO:0000313|Proteomes:UP000076852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLGA172 {ECO:0000313|EMBL:ANB72450.1,
RC ECO:0000313|Proteomes:UP000076852};
RX PubMed=27063562; DOI=10.1016/j.gene.2016.04.018;
RA Ricker N., Shen S.Y., Goordial J., Jin S., Fulthorpe R.R.;
RT "PacBio SMRT assembly of a complex multi-replicon genome reveals
RT chlorocatechol degradative operon in a region of genome plasticity.";
RL Gene 586:239-247(2016).
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DR EMBL; CP014578; ANB72450.1; -; Genomic_DNA.
DR RefSeq; WP_063495884.1; NZ_CP014578.1.
DR AlphaFoldDB; A0A160FJD5; -.
DR STRING; 1804984.AYM40_08815; -.
DR KEGG; buz:AYM40_08815; -.
DR Proteomes; UP000076852; Chromosome 1.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 2.
DR PIRSF; PIRSF000103; HIBADH; 2.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000076852}.
FT DOMAIN 2..129
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 169..218
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 221..341
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT REGION 125..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 227
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 347 AA; 34566 MW; AB651DA455317CDD CRC64;
MEIGFCGPGL MGAPMIRHLL RAGHTVHVWN RTRAKAEALL ADGAKVVDTP RELASRCEAV
LLCVADAAAV EETVFGAEGL LSVDAAAPRR VRWIVDHSSI PPAATRAFAQ RAAAVAAVAA
EGPIAATGEG GRERESAGTG TGTGTGTGTG TGTGTGTGTG TGTGTGTANV GWIDAPVSGG
VAGATAGTLA IMAGGAAADV EAVTPLLGAY SARVTRMGEV GAGQTTKLCN QTIVTATLAA
IAEAVSLAQR SGIDASRLTE GLAGGWADSV LLQIFVPRMT QSGLAPIGAF RTFQKDIDTV
AATAYETGTP MPVSSTVQQL LRLGAAMGLG EADLSAFIDV LQTARGG
//
