ID A0A160FS18_9BURK Unreviewed; 503 AA.
AC A0A160FS18;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:ANB75845.1};
GN ORFNames=AYM40_26425 {ECO:0000313|EMBL:ANB75845.1};
OS Paraburkholderia phytofirmans OLGA172.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1417228 {ECO:0000313|EMBL:ANB75845.1, ECO:0000313|Proteomes:UP000076852};
RN [1] {ECO:0000313|EMBL:ANB75845.1, ECO:0000313|Proteomes:UP000076852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLGA172 {ECO:0000313|EMBL:ANB75845.1,
RC ECO:0000313|Proteomes:UP000076852};
RX PubMed=27063562; DOI=10.1016/j.gene.2016.04.018;
RA Ricker N., Shen S.Y., Goordial J., Jin S., Fulthorpe R.R.;
RT "PacBio SMRT assembly of a complex multi-replicon genome reveals
RT chlorocatechol degradative operon in a region of genome plasticity.";
RL Gene 586:239-247(2016).
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP014579; ANB75845.1; -; Genomic_DNA.
DR RefSeq; WP_063499113.1; NZ_CP014579.1.
DR AlphaFoldDB; A0A160FS18; -.
DR STRING; 1804984.AYM40_26425; -.
DR KEGG; buz:AYM40_26425; -.
DR Proteomes; UP000076852; Chromosome 2.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ANB75845.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076852}.
FT DOMAIN 10..221
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 323..468
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 293
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 383
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 387
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 407
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 503 AA; 54251 MW; 1B36DA98B0DA8C5F CRC64;
MENRIHNSYL ASKVMSADQA AAQILPGMTV GMSGFTGSGY PKAVPLALAA QIESAHARGE
SFALKLLTGA STAPELDGAL AKVGGIDFRL PYQSDPDLRT RINRGEIEYM DIHLGQVAQY
TWFGFLGKLD MAVVEVSAIL PDGRLVPSTS VGNNKTWLDL ADKVIIEVNS AQPAGLDGMH
DIYYGTALPP ERKPIPLTGP DDRIGEPYLR VDPAKVVAVV ETHGPDRLGR FSPPDESSIQ
IANHLVEFFR HEIAMGRLGE QLLPLQSGVG NIANAVLSGL RDGGFEGLTA FTEVIQDGML
DLIRTDTIRR ASATALSLSP EGVEEFGRNI EHYRSRIVLR PQEISNHAEL VRRLGCIAIN
GMVEADIYGN VNSTHVAGSS IINGIGGSGD FARNGFLSCF VTPSTAKNGA ISCIVPMVSH
VDHTEHDVAV VVTEQGLADL RGLSPKQRAR AVINNCAHPD YRPLLQDYFE RALRASPGKH
TPHLLGEALS WHERFVASGH MKP
//
