ID   A0A160FVK7_9BURK        Unreviewed;       338 AA.
AC   A0A160FVK7;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:ANB76908.1};
GN   ORFNames=AYM40_32705 {ECO:0000313|EMBL:ANB76908.1};
OS   Paraburkholderia phytofirmans OLGA172.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=1417228 {ECO:0000313|EMBL:ANB76908.1, ECO:0000313|Proteomes:UP000076852};
RN   [1] {ECO:0000313|EMBL:ANB76908.1, ECO:0000313|Proteomes:UP000076852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OLGA172 {ECO:0000313|EMBL:ANB76908.1,
RC   ECO:0000313|Proteomes:UP000076852};
RX   PubMed=27063562; DOI=10.1016/j.gene.2016.04.018;
RA   Ricker N., Shen S.Y., Goordial J., Jin S., Fulthorpe R.R.;
RT   "PacBio SMRT assembly of a complex multi-replicon genome reveals
RT   chlorocatechol degradative operon in a region of genome plasticity.";
RL   Gene 586:239-247(2016).
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
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DR   EMBL; CP014579; ANB76908.1; -; Genomic_DNA.
DR   RefSeq; WP_063500116.1; NZ_CP014579.1.
DR   AlphaFoldDB; A0A160FVK7; -.
DR   STRING; 1804984.AYM40_32705; -.
DR   KEGG; buz:AYM40_32705; -.
DR   Proteomes; UP000076852; Chromosome 2.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:ANB76908.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076852}.
FT   DOMAIN          11..279
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   338 AA;  36503 MW;  F692C966BEBEE7FC CRC64;
     MNIWNGQHRR IYMQEVGTRD GFQAEGTFVE TRDKIALIDA LSETGMAKIE VTAFVSPQAI
     PALRDAEIVL REIERKPGVV YTALVPNMRG AERAIEARAD ELNLVMSATE SHNLSNLRMT
     REQSFNGLRQ VAASARDVGL PVNISLSCAF GCPMEGDVPT DTVIEWTQRF VEEIGARGVT
     LCDTTGMAFP QQVAALTARC IERWPQTEFT LHFHNTRGMG LANVLAAIDA GADRFDASLG
     GIGGCPYAPG ASGNVCSEEI VHALELMGYD TGVDLGALID ASKRLPALIG HDTPSQIVKA
     GRRLDLHPLP ADFAAIREPA PLRSSNCSPS AKRFAARC
//