ID A0A160NZE4_STRLU Unreviewed; 609 AA.
AC A0A160NZE4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SLA_2685 {ECO:0000313|EMBL:BAU83606.1};
OS Streptomyces laurentii.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=39478 {ECO:0000313|EMBL:BAU83606.1, ECO:0000313|Proteomes:UP000217676};
RN [1] {ECO:0000313|EMBL:BAU83606.1, ECO:0000313|Proteomes:UP000217676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31255 {ECO:0000313|EMBL:BAU83606.1,
RC ECO:0000313|Proteomes:UP000217676};
RA Doi K., Fujino Y., Nagayoshi Y., Ohshima T., Ogata S.;
RT "Complete Genome Sequence of Thiostrepton-Producing Streptomyces laurentii
RT ATCC 31255.";
RL Genome Announc. 4:e00360-16(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; AP017424; BAU83606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A160NZE4; -.
DR KEGG; slau:SLA_2685; -.
DR Proteomes; UP000217676; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:BAU83606.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:BAU83606.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217676}.
FT DOMAIN 32..158
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 161..552
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..609
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 339
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 609 AA; 65700 MW; 17A8DBD6E9B0A7CD CRC64;
MNAHPPYRDL DLIPAPREAA RRGGAPGAPD ASGAPGYVTL DERTTVDAGP GTHRTARWLR
AVLGAATGLP LADGAGPHAI RLRISADVER EHGPEGYVLS ADGSVADAAV VIEGGGPAGV
FWAAQTLRQL LGPEAHRAAR VAPAGHAWDL PSLTVTDAPR FRWRGLMLDV ARHFMPKTDV
LRQLDLMAAH KLNVLHLHLT DDQGWRVEIE RHPRLTEVGS WRARSKWGHR ESSQWNETPH
GGFYTHDDIR EIVAYAADRH ITVVPEIDLP GHSQAAIAAY PELGNGDVVD TTALPVWDTW
GVNPNVLAPT DAVLRFYEGV FEEILGLFPS PYVHIGGDEC PKDQWKASPT ARARIEELGV
GDEDGLQAWF VRHFDRWLAA RGRRLVGWDE ILEGSPAAGT PLVPLAESGT AAESGAVTEG
GAVTESGADA GPGGTTGLGL TPGATVSSWR GYAGGIAAAE AGHDVVMCPE QQVYLDHRQD
PGEDEPMPIG YVRTLADVYR FEPVPPGLSE AAAAHILGTQ ANVWTEVMEN RSRVDYQTQP
RLAAFAEVAW SELPAPDARD LAGFERRMTA HYRRLDALGV EYRPPGGPRP WQRRPGVPGR
PLEGTPPNV
//
